| Weight | 249.313 g/mol |
|---|---|
| Formula | C8H11NO4S2 |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 5 |
Erdosteine (84611-23-4, 105426-14-0)
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- Sigma-Aldrich - Erdosteine51.50 - 319.00 USD
- Fisher Scientific - Search for Erdosteine
- TCI - Erdosteine103.00 - 357.00 USD
- Protein oxidation and lipid peroxidation after renal ischemia-reperfusion injury: protective effects of erdosteine and N-acetylcysteine (Urological Research, 2006)
- Protective effects of erdosteine against doxorubicin-induced cardiomyopathy in rats. (Journal of Applied Toxicology, 2003)
- Erdosteine prevents doxorubicin-induced cardiotoxicity in rats. (Pharmacological Research, 2003)
- Oral erdosteine administration attenuates cisplatin-induced renal tubular damage in rats. (Pharmacological Research, 2003)
- In vivo evidences suggesting the role of oxidative stress in pathogenesis of vancomycin-induced nephrotoxicity: Protection by erdosteine (Toxicology, 2005)
- Assessment of the Antioxidant Activity of the SH Metabolite I of Erdosteine on Human Neutrophil Oxidative Bursts (Drug Research, 2011)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1CSC(=O)C1NC(=O)CSCC(=O)O
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InChIKeyQGFORSXNKQLDNO-UHFFFAOYSA-N
- Pubchem - Erdosteine
- Wikipedia - erdosteine
Erdosteine is a mucolytic. Specifically it is a thiol derivative developed for the treatment of chronic obstructive bronchitis, including acute infective exacerbation of chronic bronchitis. Erdosteine contains two blocked sulfhydryl groups which are released following first-pass metabolism.
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Synthesis
[(2-amino-2-oxoethyl)thio]acetic acid
+
Reactant
(Alkylation of primary amines)
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Erdosteine
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