| Weight | 265.36 g/mol |
|---|---|
| Formula | C17H19N3 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 0 |
Esmirtazapine (61337-87-9)
mirtazapine · Remeron · Rexer
Score:
#156 in Neurology
,
#697 in Neuroscience
,
#3098 in Biology
,
#3872 in Chemistry
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- Sertraline or mirtazapine for depression in dementia (HTA-SADD): a randomised, multicentre, double-blind, placebo-controlled trial (The Lancet, 2011)
- A Review of the Pharmacological and Clinical Profile of Mirtazapine (Cns Drug Reviews, 2006)
- Clinical pharmacokinetics of mirtazapine. (Clinical Pharmacokinectics, 2000)
- Tranylcypromine Versus Venlafaxine Plus Mirtazapine Following Three Failed Antidepressant Medication Trials for Depression: A STAR*D Report (American Journal of Psychiatry, 2006)
- A Comparison of Mirtazapine and Nortriptyline Following Two Consecutive Failed Medication Treatments for Depressed Outpatients: A STAR*D Report (American Journal of Psychiatry, 2006)
- The pharmacologic profile of mirtazapine (The Journal of Clinical Psychiatry, 1996)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - mirtazapine
- Remeron
- Rexer
- ORG 3770
- Remergil
- (N-methyl-11C)mirtazapine
- Norset
- ORG-3770
- Mundogen brand of mirtazapine
- Org 50081
- Organon brand of mirtazapine
- Celltech brand of mirtazapine
- 6-azamianserin
- Zispin
-
SMILESCN1CCN2C(C1)C3=CC=CC=C3CC4=C2N=CC=C4
-
InChIKeyRONZAEMNMFQXRA-UHFFFAOYSA-N
- Pubchem - Esmirtazapine
- Wikipedia - esmirtazapine
Esmirtazapine (ORG-50,081) is a drug which was under development by Organon for the treatment of insomnia and vasomotor symptoms (e.g., hot flashes) associated with menopause. Esmirtazapine is the (S)-(+)-enantiomer of mirtazapine and possesses similar overall pharmacology, including inverse agonist actions at H1 and 5-HT2 receptors and antagonist actions at 2-adrenergic receptors. As of March 2010, Merck terminated internal clinical development program for esmirtazapine, for hot flashes and insomnia, for strategic reasons.
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