| Weight | 440.411 g/mol |
|---|---|
| Formula | C23H31Cl2NO3 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 5 |
estramustine (2998-57-4)
Emcyt · Estracyt · Estramustine Phosphate Sodium
Score:
#26 in Molecular and cellular biology
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#982 in Biochemistry
,
#2586 in Biology
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#3226 in Chemistry
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- Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer (The New England Journal of Medicine, 2004)
- Phase I Trial of Docetaxel With Estramustine in Androgen-Independent Prostate Cancer (Journal of Clinical Oncology, 1999)
- Phase II Study of Docetaxel, Estramustine, and Low-Dose Hydrocortisone in Men With Hormone-Refractory Prostate Cancer: A Final Report of CALGB 9780 (Journal of Clinical Oncology, 2001)
- Phase II trial of 96-hour paclitaxel plus oral estramustine phosphate in metastatic hormone-refractory prostate cancer. (Journal of Clinical Oncology, 1997)
- Phase II study of estramustine and vinblastine, two microtubule inhibitors, in hormone-refractory prostate cancer (Journal of Clinical Oncology, 1992)
- Phase II evaluation of oral estramustine and oral etoposide in hormone-refractory adenocarcinoma of the prostate. (Journal of Clinical Oncology, 1994)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Emcyt
- Estracyt
- Estramustine Phosphate Sodium
- Estramustin Phosphate
- NSC 89199
- Leo275
- NSC-89199
- Estramustinphosphate
- NSC89199
- Leo 275
- Leo-275
-
SMILESCC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)OC(=O)N(CCCl)CCCl
-
InChIKeyFRPJXPJMRWBBIH-UHFFFAOYSA-N
- Pubchem - estramustine
- Wikipedia - estramustine
Estramustine (INN, USAN, BAN) is a synthetic, steroidal estrogen and alkylating antineoplastic agent which was never marketed. It is an estrogen ester specifically, the C3 normustine ester of estradiol and acts as a prodrug to estradiol and normustine in the body. Estramustine phosphate, the C17 phosphate ester of estramustine, is marketed and used in the treatment of prostate cancer.
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