| Weight | 340.851 g/mol |
|---|---|
| Formula | C17H25ClN2O3 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 6 |
Eticlopride (84226-12-0)
Score:
#1194 in Neuroscience
,
#5142 in Biology
,
#6701 in Chemistry
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- Some in vitro receptor binding properties of [3H]eticlopride, a novel substituted benzamide, selective for dopamine-D2 receptors in the rat brain (European Journal of Pharmacology, 1985)
- Nicotine potentiation of brain stimulation reward reversed by DHE and SCH 23390, but not by eticlopride, LY 314582 or MPEP in rats (Psychopharmacology, 2002)
- The effects of eticlopride and naltrexone on responding maintained by food, cocaine, heroin and cocaine/heroin combinations in rats. (Journal of Pharmacology and Experimental Therapeutics, 1996)
- Regional in vivo binding of the substituted benzamide [3H]eticlopride in the rat brain: Evidence for selective labelling of dopamine receptors (European Journal of Pharmacology, 1986)
- Carbon-11 labelling of eticlopride in two different positions--a selective high-affinity ligand for the study of dopamine D-2 receptors using PET. (International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes, 1990)
- D-amphetamine facilitation of morris water task performance is blocked by eticlopride and correlated with increased dopamine synthesis in the prefrontal cortex. (Behavioural Brain Research, 2000)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCCC1=CC(=C(C(=C1O)C(=O)NCC2CCCN2CC)OC)Cl
-
InChIKeyAADCDMQTJNYOSS-UHFFFAOYSA-N
- Pubchem - Eticlopride
- Wikipedia - eticlopride
Eticlopride is a selective dopamine antagonist that acts on D2 dopamine receptor. It is primarily used in pharmacological research.
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5-chloro-3-ethyl-6-methoxysalicyloyl chloride
+
2-(Aminomethyl)-1-ethylpyrrolidine
(Schotten-Baumann amide from acid)
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