| Weight | 585.616 g/mol |
|---|---|
| Formula | C25H36N3O9PS |
| Hydrogen Acceptors | 8 |
| Hydrogen Donors | 4 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 13 |
Fosamprenavir (226700-79-4)
Score:
#1 in HIV/AIDS
,
#10 in Virology
,
#138 in Microbiology
,
#1450 in Biology
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- The KLEAN study of fosamprenavir-ritonavir versus lopinavir-ritonavir, each in combination with abacavir-lamivudine, for initial treatment of HIV infection over 48 weeks : a randomised non-inferiority trial (The Lancet, 2006)
- SOLO: 48-week efficacy and safety comparison of once-daily fosamprenavir /ritonavir versus twice-daily nelfinavir in naive HIV-1-infected patients. (AIDS, 2004)
- Fosamprenavir or atazanavir once daily boosted with ritonavir 100 mg, plus tenofovir/emtricitabine, for the initial treatment of HIV infection: 48-week results of ALERT (Aids Research and Therapy, 2008)
- Effects of atazanavir/ritonavir or fosamprenavir/ritonavir on the pharmacokinetics of rosuvastatin. (Journal of Cardiovascular Pharmacology, 2008)
- Fosamprenavir : clinical pharmacokinetics and drug interactions of the amprenavir prodrug. (Clinical Pharmacokinectics, 2006)
- Combining fosamprenavir with lopinavir/ritonavir substantially reduces amprenavir and lopinavir exposure: ACTG protocol A5143 results (AIDS, 2005)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC(C)CN(CC(C(CC1=CC=CC=C1)NC(=O)OC2CCOC2)OP(=O)(O)O)S(=O)(=O)C3=CC=C(C=C3)N
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InChIKeyMLBVMOWEQCZNCC-UHFFFAOYSA-N
- Pubchem - Fosamprenavir
- Wikipedia - fosamprenavir
Fosamprenavir (marketed by ViiV Healthcare as the calcium salt under the trade names Lexiva in the U.S. and Telzir in Europe) is a drug for the treatment of HIV infections. It is a pro-drug of the protease inhibitor and antiretroviral drug amprenavir.
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