| Weight | 891.54 g/mol |
|---|---|
| Formula | C30H60I3N3O3 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 21 |
GALLAMINE TRIETHIODIDE (65-29-2)
Gallamine · Flaxedil · Gallamine Triethyl Iodide
Score:
#446 in Neuroscience
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#2051 in Biology
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#2507 in Chemistry
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- Modification of the binding properties of muscarinic receptors by gallamine. (Molecular Pharmacology, 1983)
- The inhibitory effect of gallamine on muscarinic receptors. (British Journal of Pharmacology, 1976)
- Pain responses to perineuromal injection of normal saline, gallamine, and lidocaine in humans. (Pain, 1989)
- The pharmacology of Flaxedil, with observations on certain analogs. (Annals of the New York Academy of Sciences, 1951)
- Antimuscarinic action of methoctramine, a new cardioselective M-2 muscarinic receptor antagonist alone and in combination with atropine and gallamine (European Journal of Pharmacology, 1987)
- Role of acidic amino acids in the allosteric modulation by gallamine of antagonist binding at the m2 muscarinic acetylcholine receptor. (Molecular Pharmacology, 1994)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Gallamine
- Flaxedil
- Gallamine Triethyl Iodide
- Gallamine Triethochloride
- Gallamonium Iodide
-
SMILESCC[N+](CC)(CC)CCOC1=C(C(=CC=C1)OCC[N+](CC)(CC)CC)OCC[N+](CC)(CC)CC.[I-].[I-].[I-]
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- Pubchem - GALLAMINE TRIETHIODIDE
- Wikipedia - gallamine triethiodide
Gallamine triethiodide (Flaxedil) is a non-depolarising muscle relaxant. It acts by combining with the cholinergic receptor sites in muscle and competitively blocking the transmitter action of acetylcholine. Gallamine triethiodide has a parasympatholytic effect on the cardiac vagus nerve which causes tachycardia and occasionally hypertension.
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Synthesis
Reactant
+
AC1N0J2C
(Williamson ether)
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GALLAMINE TRIETHIODIDE
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