| Weight | 355.434 g/mol |
|---|---|
| Formula | C21H25NO4 |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 4 |
Glaucine (475-81-0)
glaucine phosphate (5:7), (+-)-isomer · glaucine acetate, (+-)-isomer · glaucine phosphate (2:3), (S)-isomer
Score:
#2303 in Biochemistry
,
#5836 in Chemistry
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- Phtochemical routes to aporphines. New synthesis of nuciferine and glaucine. (Journal of Organic Chemistry, 1970)
- The inhibitory effects of boldine, glaucine, and probucol on TPA-induced down regulation of gap junction function: Relationships to intracellular peroxides, protein kinase C translocation, and connexin 43 phosphorylation (Biochemical Pharmacology, 1995)
- Bronchodilator and anti-inflammatory activities of glaucine: In vitro studies in human airway smooth muscle and polymorphonuclear leukocytes (British Journal of Pharmacology, 1999)
- Chiral auxiliary mediated pictet-spengler reactions: Asymmetric syntheses of ()-laudanosine, (+)-glaucine and ()-xylopinine (Tetrahedron, 1997)
- Ionic liquid-supported solidliquid extraction of bioactive alkaloids. II. Kinetics, modeling and mechanism of glaucine extraction from Glaucium flavum Cr. (Papaveraceae) (Separation and Purification Technology, 2013)
- Multiple actions of glaucine on cyclic nucleotide phosphodiesterases, 1-adrenoceptor and benzothiazepine binding site at the calcium channel (British Journal of Pharmacology, 1992)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - glaucine phosphate (5:7), (+-)-isomer
- glaucine acetate, (+-)-isomer
- glaucine phosphate (2:3), (S)-isomer
- tussiglaucin
- glaucine hydrochloride, (S)-isomer
- glaucine maleate, (+-)-isomer
- glaucine citrate, (+-)-isomer
- glaucine, (S)-isomer
- glaucine tartrate, (S)-isomer
- glaucine, (R)-isomer
- glaucine phosphate
- glaucine sulphate, (+-)-isomer
- glaucine hydrobromide, (S)-isomer
- glaucine hydrochloride, (+-)-isomer
- glaucine phosphate (2:3), (R)-isomer
- glaucine phosphate, (S)-isomer
- glaucine tartrate (1:1), (+-)-isomer
- glaucine phosphate (2:3), (+-)-isomer
- glaucine tartrate (1:1), (R)-isomer
- glaucine hydrobromide, (+-)-isomer
- glaucine phosphate (5:8), (+-)-isomer
- glaucine tartrate (1:1), (S)-isomer
- glaucine hydrobromide, (R)-isomer
- glaucine tartrate, (R)-isomer
- glaucine hydrochloride, (R)-isomer
- glaucine hydroiodide, (S)-isomer
- glaucine tartrate, (+-)-isomer
- glaucine mesylate, (+-)-isomer
- glaucine hydroiodide, (R)-isomer
- glaucine tosylate, (R)-isomer
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SMILESCN1CCC2=CC(=C(C3=C2C1CC4=CC(=C(C=C43)OC)OC)OC)OC
-
InChIKeyRUZIUYOSRDWYQF-UHFFFAOYSA-N
- Pubchem - Glaucine
- Wikipedia - glaucine
Glaucine is an alkaloid found in several different plant species in the Papaveraceae family such as Glaucium flavum, Glaucium oxylobum and Corydalis yanhusuo, and in other plants like Croton lechleri in the family Euphorbiaceae. It has bronchodilator and antiinflammatory effects, acting as a PDE4 inhibitor and calcium channel blocker, and is used medically as an antitussive in some countries. Glaucine may produce side effects such as sedation, fatigue, and a hallucinogenic effect characterised by colourful visual images, and has been detected as a novel psychoactive drug.
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