| Weight | 158.113 g/mol |
|---|---|
| Formula | C5H6N2O4 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 1 |
hydroorotic acid (155-54-4)
dihydroorotate · 4,5-dihydroorotic acid, (D)-isomer · 4,5-dihydroorotic acid
Score:
#1891 in Biochemistry
,
#4049 in Biology
,
#5101 in Chemistry
"What do you need help with?"
LabBot
- Sigma-Aldrich - hydroorotic acid67.50 - 356.50 USD
- Fisher Scientific - Search for hydroorotic acid
- TCI - Search for hydroorotic acid
- The immunosuppressive metabolite of leflunomide is a potent inhibitor of human dihydroorotate dehydrogenase (Biochemistry, 1996)
- Dihydroorotate Dehydrogenase Is a High Affinity Binding Protein for A77 1726 and Mediator of a Range of Biological Effects of the Immunomodulatory Compound (Journal of Biological Chemistry, 1995)
- Structures of human dihydroorotate dehydrogenase in complex with antiproliferative agents. (Structure, 2000)
- Inhibition of dihydroorotate dehydrogenase by the immunosuppressive agent leflunomide. (Biochemical Pharmacology, 1995)
- Structure-guided lead optimization of triazolopyrimidine-ring substituents identifies potent Plasmodium falciparum dihydroorotate dehydrogenase inhibitors with clinical candidate potential (Journal of Medicinal Chemistry, 2011)
- Conversion of dihydroorotate to orotate in parasitic protozoa. (Biochimica et Biophysica Acta, 1979)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - dihydroorotate
- 4,5-dihydroorotic acid, (D)-isomer
- 4,5-dihydroorotic acid
- 4,5-dihydroorotic acid, (L)-isomer
- 5,6-dihydroorotate
- 4,5-dihydroorotic acid, (DL)-isomer
- L-dihydroorotate
-
SMILESC1C(NC(=O)NC1=O)C(=O)O
-
InChIKeyUFIVEPVSAGBUSI-UHFFFAOYSA-N
- Pubchem - hydroorotic acid
- Wikipedia - DL-hydroorotic acid
4,5-Dihydroorotic acid is a derivative of orotic acid which serves as an intermediate in pyrimidine biosynthesis.
Suppliers
Most-cited Publications
Areas of Application
Safety
Alternate Names
External Links
Similar Compounds
2-ketoglutaric acid
(34410-46-3, 328-50-7, 17091-15-5, 997-43-3)
8 alternate names
3 suppliers
2-Methylsuccinic acid
(498-21-5)
8 alternate names
3 suppliers
Itaconic acid
(97-65-4, 25119-64-6)
8 alternate names
1 safety hazard
3 suppliers
6-Hydroxynicotinic acid
(5006-66-6)
8 alternate names
3 suppliers
N-methyl-D-aspartic acid
(6384-92-5)
8 alternate names
3 suppliers
ETHYLMALONIC ACID
(601-75-2)
8 alternate names
3 suppliers
3-Ureidopropionic acid
(462-88-4)
8 alternate names
3 suppliers
piracetam
(7491-74-9)
8 alternate names
3 suppliers
piperidine-2-carboxylic acid
(535-75-1, 4043-87-2)
8 alternate names
3 suppliers
oxalacetic acid
(328-42-7)
8 alternate names
3 suppliers
3-Methyl-2-oxovaleric acid
(1460-34-0, 39748-49-7)
8 alternate names
3 suppliers
l-Pipecolic acid
(3105-95-1)
8 alternate names
3 suppliers
2-METHYLGLUTARIC ACID
(18069-17-5, 617-62-9)
8 alternate names
3 suppliers
(R)-Piperidine-2-carboxylic acid
(1723-00-8)
8 alternate names
3 suppliers
Glutaconic acid
(628-48-8, 505-36-2, 1724-02-3)
8 alternate names
3 suppliers
2-Methylbutyrylglycine
(52320-67-9)
8 alternate names
3 suppliers
3-METHYLGLUTARIC ACID
(626-51-7)
8 alternate names
3 suppliers
3-oxobutan-2-yl acetate
(4906-24-5)
8 alternate names
3 suppliers
adipic acid
(124-04-9, 25666-61-9)
8 alternate names
3 safety hazards
3 suppliers
Cyclamic acid
(100-88-9)
8 alternate names
3 suppliers
CYMOXANIL
(57966-95-7)
8 alternate names
5 safety hazards
3 suppliers
CYANURIC ACID
(108-80-5, 40580-20-9, 27026-93-3)
8 alternate names
3 suppliers
ACESULFAME
(33665-90-6)
8 alternate names
3 suppliers
allantoin
(97-59-6)
8 alternate names
3 suppliers
Daminozide
(1596-84-5)
8 alternate names
3 suppliers
cis-Aconitic acid
(585-84-2, 499-12-7)
8 alternate names
3 suppliers
1,2-Diacetoxypropane
(623-84-7)
8 alternate names
3 suppliers
Isobutyric anhydride
(97-72-3)
8 alternate names
3 safety hazards
3 suppliers
METHACRYLIC ANHYDRIDE
(760-93-0)
8 alternate names
3 suppliers
N-CHLOROSUCCINIMIDE
(128-09-6)
8 alternate names
3 suppliers
trans-Aconitic acid
(499-12-7, 4023-65-8)
8 alternate names
3 suppliers
picolinic acid
(32075-31-3, 98-98-6, 88161-53-9)
8 alternate names
3 suppliers
bemegride
(64-65-3)
8 alternate names
3 suppliers
5-Hydroxymethyluracil
(4433-40-3)
8 alternate names
3 suppliers
2-FUROIC ACID
(88-14-2, 26447-28-9)
8 alternate names
3 suppliers
urocanic acid
(3465-72-3, 104-98-3)
8 alternate names
3 suppliers
BARBITURIC ACID
(67-52-7, 4390-16-3)
8 alternate names
3 suppliers
3-Hydroxybenzoic acid
(99-06-9, 10476-50-3)
8 alternate names
3 suppliers
3,3'-Thiodipropionic acid
(111-17-1)
8 alternate names
2 safety hazards
3 suppliers
Imidazole-4-acetic acid
(645-65-8)
8 alternate names
3 suppliers
N-Isovaleroylglycine
(16284-60-9)
8 alternate names
3 suppliers
4,6-DIOXOHEPTANOIC ACID
(51568-18-4)
8 alternate names
3 suppliers
Rocryl 410
(4664-49-7)
8 alternate names
3 suppliers
tiopronin
(1953-02-2)
8 alternate names
3 suppliers
2-Oxoadipic acid
(3184-35-8)
8 alternate names
3 suppliers
CYCLOHEXANECARBOXYLIC ACID
(50825-29-1, 98-89-5)
8 alternate names
3 suppliers
2,4-Diamino-6-hydroxypyrimidine
(56-06-4)
8 alternate names
3 suppliers
4771-80-6
(4771-80-6, 1338-24-5)
8 alternate names
3 suppliers
2,2-DIMETHYLSUCCINIC ACID
(597-43-3)
8 alternate names
3 suppliers
Glyphosate
(1071-83-6)
8 alternate names
3 safety hazards
3 suppliers
hydroorotic acid
CAS Directory
