| Weight | 307.39 g/mol |
|---|---|
| Formula | C17H25NO4 |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 7 |
Ibopamine (66195-31-1)
SB 7505 · Escandine · N-methyldopamine diisobutyrate
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- Randomised study of effect of ibopamine on survival in patients with advanced severe heart failure (The Lancet, 1997)
- Double-blind placebo-controlled study of ibopamine and digoxin in patients with mild to moderate heart failure: results of the Dutch Ibopamine Multicenter Trial (DIMT). (Journal of the American College of Cardiology, 1993)
- Progression of left ventricular dysfunction secondary to coronary artery disease, sustained neurohormonal activation and effects of ibopamine therapy during long-term therapy with angiotensin-converting enzyme inhibitor (American Journal of Cardiology, 1994)
- Effects of long-term therapy with oral ibopamine on resting hemodynamics and exercise capacity in patients with heart failure: relationship to the generation of N-methyldopamine and to plasma norepinephrine levels. (Circulation, 1986)
- Heart rate variability in patients with mild to moderate heart failure: Effects of neurohormonal modulation by digoxin and ibopamine (Journal of the American College of Cardiology, 1995)
- The effects of oral ibopamine in patients with mild heart failure a double blind placebo controlled comparison to furosemide (International Journal of Cardiology, 1993)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - SB 7505
- Escandine
- N-methyldopamine diisobutyrate
- Inopamil
- ibopamine hydrochloride
- SB-7505
-
SMILESCC(C)C(=O)OC1=C(C=C(C=C1)CCNC)OC(=O)C(C)C
-
InChIKeyWDKXLLJDNUBYCY-UHFFFAOYSA-N
- Pubchem - Ibopamine
- Wikipedia - ibopamine
Ibopamine is a sympathomimetic drug, designed as a prodrug of epinine, used in ophthalmology. It induces mydriasis. It also has been investigated for use in the treatment of congestive heart failure.
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Synthesis
Isobutyryl chloride
+
Reactant
(O-acylation)
Reactant
+
(2-chloroethyl)methylamine
(Friedel-Crafts alkylation)
Reactant
+
2-Methylperoxypropionic acid
(Dakin oxidation)
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