| Weight | 268.229 g/mol |
|---|---|
| Formula | C10H12N4O5 |
| Hydrogen Acceptors | 8 |
| Hydrogen Donors | 4 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 2 |
inosine (58-63-9)
Score:
#935 in Biochemistry
,
#2470 in Biology
,
#3082 in Chemistry
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- Redirection of Silencing Targets by Adenosine-to-Inosine Editing of miRNAs (Science, 2007)
- Extracellular Adenosine, Inosine, Hypoxanthine, and Xanthine in Relation to Tissue Nucleotides and Purines in Rat Striatum During Transient Ischemia (Journal of Neurochemistry, 1987)
- Structure and Mechanism of Inosine Monophosphate Dehydrogenase in Complex with the Immunosuppressant Mycophenolic Acid (Cell, 1996)
- Some reactions of adenosine and inosine phosphates in animal tissues (Biochimica et Biophysica Acta, 1953)
- Adverse drug reactions to azathioprine therapy are associated with polymorphism in the gene encoding inosine triphosphate pyrophosphatase (ITPase). (Pharmacogenetics, 2004)
- Inosine exists in mRNA at tissue-specific levels and is most abundant in brain mRNA. (The EMBO Journal, 1998)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)CO)O)O
-
InChIKeyUGQMRVRMYYASKQ-UHFFFAOYSA-N
- Pubchem - inosine
- Wikipedia - inosine
Inosine is a nucleoside that is formed when hypoxanthine is attached to a ribose ring (also known as a ribofuranose) via a -N9-glycosidic bond. Inosine is commonly found in tRNAs and is essential for proper translation of the genetic code in wobble base pairs. Knowledge of inosine metabolism has led to advances in immunotherapy in recent decades.
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