iproniazid (54-92-2)

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  0.25 g
  $41.00

  1 g
  $70.00

  5 g
  $140.00

Most-cited Publications

• Effects of amino acid feedings in schizophrenic patients treated with iproniazid. (Science, 1961)
• Effects of iproniazid in depressive syndromes. (BMJ, 1959)
• Isoniazid and iproniazid: activation of metabolites to toxic intermediates in man and rat (Science, 1976)
• A clinical and pharmacodynamic evaluation of iproniazid as a psychic energizer. (Psychiatric research reports, 1957)
• A CLINICAL AND BIOCHEMICAL STUDY OF A TRIAL OF IPRONIAZID IN THE TREATMENT OF DEPRESSION (Journal of Neurology, Neurosurgery, and Psychiatry, 1959)
• THE EFFECTS OF TRYPTAMINE ON THE CENTRAL NERVOUS SYSTEM,INCLUDING A PHARMACOLOGICAL PROCEDURE FOR THE EVALUATION OF IPRONIAZID-LIKE DRUGS (Journal of Pharmacology and Experimental Therapeutics, 1959)

Areas of Application

Safety

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Trends

Alternate Names

• Iprazid
• SMILES
  CC(C)NNC(=O)C1=CC=NC=C1
• InChIKey
  NYMGNSNKLVNMIA-UHFFFAOYSA-N

External Links

• Pubchem - iproniazid
• Wikipedia - iproniazid
  Iproniazid (Marsilid, Rivivol, Euphozid, Iprazid, Ipronid, Ipronin) is a non-selective, irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class. It was discontinued in most of the world in the 1960s, but remained in use in France until fairly recently. Iproniazid was originally developed for the treatment of tuberculosis, but in 1952, its antidepressant properties were discovered when researchers noted that patients given isoniazid became inappropriately happy.

Synthesis

isoniazid  +  2-CHLOROPROPANE (Alkylation of primary amines)

Pyridine-4-carbonyl chloride  +  1-Isopropylhydrazine (Schotten-Baumann amide from acid)

Synthesis of iproniazid ›

Similar Compounds

Isonicotinamide (1453-82-3)

2 alternate names

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58481-01-9 (58481-01-9)

2 alternate names

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58481-04-2 (58481-04-2)

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Isonicotinamide 1-oxide (38557-82-3)

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2,6-Dichloroisonicotinohydrazide (57803-51-7)

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N-(2-Aminoethyl)isonicotinamide (17704-88-0)

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4-Pyridinecarboxamide, N-(4-pyridinylmethyl)- (28489-58-9)

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N-(tert-butyl)isonicotinamide (65321-30-4)

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N-(2-Hydroxyethyl)isonicotinamide (6265-74-3)

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2-methylpyridine-4-carboxamide (19354-04-2)

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Isonicotinylglycine (2015-20-5)

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2-Methoxyisonicotinohydrazide (19353-97-0)

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2-IODOISONICOTINAMIDE (29840-76-4)

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2-Amino-isonicotinamide (13538-42-6)

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n-benzylisonicotinamide (6320-63-4)

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4-chloro-N'-(2-chloroacetyl)benzohydrazide (50677-27-5)

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N,N-Bis(2-hydroxyethyl)-4-pyridinecarboxamide (70892-82-9)

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Nicotinohydrazide (553-53-7)

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2-chloro-N-methylisonicotinamide (131418-11-6)

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2-CHLORO-N-ETHYLISONICOTINAMIDE (131418-17-2)

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2-CHLORO-N-ISOPROPYLISONICOTINAMIDE (439931-33-6)

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N-Phenylisonicotinamide (3034-31-9)

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2-benzoylhydrazinecarbothioamide (5351-66-6, 53818-41-0)

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4-Pyridinecarboxaldehyde (872-85-5)

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3731-53-1 (3731-53-1)

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1-isonicotinoyl-4-piperidinone hydrochloride (1269199-40-7)

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N-(4-pyridinylmethyl)-1-propanamine (70065-81-5)

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4-(Ethylaminomethyl)pyridine (33403-97-3)

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N-(4-Amino-phenyl)-isonicotinamide (13116-08-0)

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2-chloro-N-cyclopropylisonicotinamide (959241-13-5)

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quinoline-6-carbohydrazide (5382-47-8)

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4-cyanobenzohydrazide (43038-36-4)

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4-(hydrazinocarbonyl)benzamide (22590-92-7)

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3619-22-5 (3619-22-5)

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Terephthalic acid dihydrazide (136-64-1)

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tert-butyl(4-pyridinylmethyl)amine hydrochloride (1185150-94-0)

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N-(4-pyridinylmethyl)cyclopropanamine dihydrochloride (1609403-18-0)

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Cyclopropyl-pyridin-4-ylmethyl-amine (193153-60-5)

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2-methyl-N-(4-pyridinylmethyl)-1-propanamine (869941-71-9)

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ISONICOTINAMIDINE (33278-46-5)

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2-methylquinoline-4-carbohydrazide (29620-66-4)

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6971-44-4 (6971-44-4)

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Methylpyridin-4-ylmethylamine dihydrochloride (128739-16-2)

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(R)-1-(4-PYRIDYL)ETHYLAMINE (50392-78-4)

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3-[(4-pyridylmethyl)amino]propanenitrile (648409-30-7)

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4-isopropylbenzohydrazide (5351-24-6)

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N'-(2-chloroacetyl)-2-hydroxybenzohydrazide (28669-13-8)

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N-(4-Pyridinylmethyl)acetamide (23974-15-4)

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3-[(4-pyridinylmethyl)amino]-1-propanol hydrochloride (1216431-19-4)

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Gapicomine (1539-39-5)

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1H-indole-3-carbohydrazide (15317-58-5)

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4-Acetylpyridine (1122-54-9)

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4-ethylbenzohydrazide (64328-55-8)

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N-(4-pyridinylmethyl)-2-propen-1-amine (532407-09-3)

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4-(1-pyrrolidinylcarbonyl)-2-pyridinamine (1060817-34-6)

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4-pyridinemethanamine, N,N-dimethyl- (38222-85-4)

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4-Chlorobenzhydrazide (536-40-3)

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2-Naphthhydrazide (39627-84-4)

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3,5-dimethylbenzohydrazide (27389-49-7)

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m-Toluic acid hydrazide (13050-47-0)

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3-Methylbenzohydrazide (13050-47-0)

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105101-25-5 (105101-25-5)

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Thioisonicotinamide (2196-13-6)

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N-methyl-N-(4-pyridinylmethyl)glycine dihydrochloride (1390654-31-5)

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2,6-dimethylquinoline-4-carbohydrazide (613656-68-1)

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4-Fluorobenzhydrazide (456-06-4)

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2-bromo-4-(1-pyrrolidinylcarbonyl)pyridine (892548-11-7)

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4-Aminobenzohydrazide (5351-17-7)

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1,2-Dibenzoyl-1-methylhydrazine (21150-15-2)

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4-iodobenzohydrazide (39115-95-2)

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4-tert-Butylbenzhydrazide (43100-38-5)

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Isophthalic dihydrazide (2760-98-7)

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Benzoic acid, (2-methylpropylidene)hydrazide (63494-84-8)

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4-Bromobenzohydrazide (5933-32-4)

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Isonicotinoyl chloride hydrochloride (39178-35-3)

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N'-Benzoyl-N,N'-dimethylbenzohydrazide (1226-43-3)

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6-bromo-2-methylquinoline-4-carbohydrazide (215778-63-5)

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Di(pyridin-4-yl)methanone (6918-15-6)

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ISONICOTINIC ACID (55-22-1)

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3,4-Dimethylbenzohydrazide (42596-61-2)

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Cyclopentyl-pyridin-4-ylmethyl-amine (626210-39-7)

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2-Methylbenzohydrazide (7658-80-2)

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Nicotinamide hydroiodide (3726-23-6)

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AC1LIT4G (869942-13-2)

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Ambcb9019007 (1158735-57-9)

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2-Aminonicotinohydrazide (5327-31-1)

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Ambcb9027527 (1158213-35-4)

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1-isonicotinoylpiperidine-4-carboxylic acid (67691-60-5)

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2-chloro-4-(1-piperidinylcarbonyl)pyridine (90287-80-2)

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4-hydroxybenzhydrazide (5351-23-5)

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3-Bromobenzhydrazide (39115-96-3)

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4-(Trifluoromethyl)benzhydrazide (339-59-3)

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1-(2-chloroisonicotinoyl)-4-methylpiperazine hydrochloride (1185294-13-6)

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3 suppliers

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iproniazid

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