| Weight | 586.689 g/mol |
|---|---|
| Formula | C33H38N4O6 |
| Hydrogen Acceptors | 9 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 4 |
irinotecan (97682-44-5, 100286-90-6)
Score:
#151 in Biochemistry
,
#649 in Biology
,
#693 in Chemistry
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- Bevacizumab plus Irinotecan, Fluorouracil, and Leucovorin for Metastatic Colorectal Cancer (The New England Journal of Medicine, 2004)
- Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer (The New England Journal of Medicine, 2004)
- Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial. (The Lancet, 2000)
- Irinotecan plus Fluorouracil and Leucovorin for Metastatic Colorectal Cancer (The New England Journal of Medicine, 2000)
- A Randomized Controlled Trial of Fluorouracil Plus Leucovorin, Irinotecan, and Oxaliplatin Combinations in Patients With Previously Untreated Metastatic Colorectal Cancer (Journal of Clinical Oncology, 2004)
- Bevacizumab Alone and in Combination With Irinotecan in Recurrent Glioblastoma (Journal of Clinical Oncology, 2009)
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SMILESCCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7
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- Pubchem - irinotecan
- Wikipedia - irinotecan
Irinotecan, sold under the brand name Camptosar among others, is a medication used to treat colon cancer and small cell lung cancer. For colon cancer it is used either alone or with fluorouracil. For small cell lung cancer it is used with cisplatin.
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irinotecan
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