| Weight | 309.434 g/mol |
|---|---|
| Formula | C19H19NOS |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 0 |
ketotifen (34580-14-8, 34580-13-7)
Ketotifen Fumarate · Zaditen · Ketotiphen
Score:
#621 in Biochemistry
,
#1790 in Biology
,
#2130 in Chemistry
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- The mast cell stabiliser ketotifen decreases visceral hypersensitivity and improves intestinal symptoms in patients with irritable bowel syndrome (Gut, 2010)
- The pharmacological properties of a new, orally active antianaphylactic compound: ketotifen, a benzocycloheptathiophene. (Drug Research, 1978)
- Terbutaline-induced desensitization of human lymphocyte beta 2-adrenoceptors. Accelerated restoration of beta-adrenoceptor responsiveness by prednisone and ketotifen. (Journal of Clinical Investigation, 1985)
- Prevention of asthma by ketotifen in infants with atopic dermatitis. (Annals of allergy, 1992)
- Prevention of Mast-Cell Degranulation by Ketotifen in Patients with Physical Urticarias (Annals of Internal Medicine, 1986)
- Gastric mucosal damage by ethanol is mediated by substance P and prevented by ketotifen, a mast cell stabilizer (Gastroenterology, 1991)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Ketotifen Fumarate
- Zaditen
- Ketotiphen
- Ketotifene
- 4,9-Dihydro-4-(1-methyl-4-piperidylidene)-10H-benzo(4,5)-cyclohepta(1,2-b)thiophen-10-one
- Ketotiphene
-
SMILESCN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1
-
InChIKeyZCVMWBYGMWKGHF-UHFFFAOYSA-N
- Pubchem - ketotifen
- Wikipedia - ketotifen
Ketotifen, sold under the brand name Zaditor among others, is a first-generation noncompetitive H1-antihistamine and mast cell stabilizer. It is most commonly sold as a salt with fumaric acid, ketotifen fumarate, and is available in two forms. In its ophthalmic form, it is used to treat allergic conjunctivitis.
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