| Weight | 270.21 g/mol |
|---|---|
| Formula | C12H9F3N2O2 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 2 |
leflunomide (75706-12-6)
Arava · HWA 486 · Aventis Pharma Brand of Leflunomide
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- Efficacy and safety of leflunomide compared with placebo and sulphasalazine in active rheumatoid arthritis: a double-blind, randomised, multicentre trial (The Lancet, 1999)
- Treatment of Active Rheumatoid Arthritis With Leflunomide Compared With Placebo and Methotrexate (JAMA Internal Medicine, 1999)
- A comparison of the efficacy and safety of leflunomide and methotrexate for the treatment of rheumatoid arthritis (Rheumatology, 2000)
- Concomitant Leflunomide Therapy in Patients with Active Rheumatoid Arthritis despite Stable Doses of Methotrexate: A Randomized, Double-Blind, Placebo-Controlled Trial (Annals of Internal Medicine, 2002)
- Efficacy and safety of leflunomide in the treatment of psoriatic arthritis and psoriasis: A multinational, doubleblind, randomized, placebocontrolled clinical trial (Arthritis & Rheumatism, 2004)
- Leflunomide: mode of action in the treatment of rheumatoid arthritis (Annals of the Rheumatic Diseases, 2000)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Arava
- HWA 486
- Aventis Pharma Brand of Leflunomide
- Aventis Brand of Leflunomide
- HWA-486
- Aventis Behring Brand of Leflunomide
- N-(4-trifluoromethyphenyl)-5-methylisoxazole-4-carboxamide
- SU101
- Hoechst Brand of Leflunomide
-
SMILESCC1=C(C=NO1)C(=O)NC2=CC=C(C=C2)C(F)(F)F
-
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- Pubchem - leflunomide
- Wikipedia - leflunomide
Leflunomide (original brand name Arava) is an immunosuppressive disease-modifying antirheumatic drug (DMARD), used in active moderate-to-severe rheumatoid arthritis and psoriatic arthritis. It is a pyrimidine synthesis inhibitor that works by inhibiting dihydroorotate dehydrogenase.
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leflunomide
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