| Weight | 311.338 g/mol |
|---|---|
| Formula | C14H21N3O5 |
| Hydrogen Acceptors | 6 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 8 |
Leonurine (24697-74-3)
Score:
#2878 in Biochemistry
,
#5334 in Biology
,
#7041 in Chemistry
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- Leonurine Protects Middle Cerebral Artery Occluded Rats Through Antioxidant Effect and Regulation of Mitochondrial Function (Stroke, 2010)
- Neuroprotective Effects of Leonurine on Ischemia/Reperfusion-Induced Mitochondrial Dysfunctions in Rat Cerebral Cortex (Biological & Pharmaceutical Bulletin, 2010)
- Protective effects of leonurine in neonatal rat hypoxic cardiomyocytes and rat infarcted heart. (Clinical and Experimental Pharmacology and Physiology, 2009)
- Endothelium-independent vasorelaxation by leonurine, a plant alkaloid purified from Chinese motherwort (Life Sciences, 2001)
- Herba leonurine attenuates doxorubicin-induced apoptosis in H9c2 cardiac muscle cells. (European Journal of Pharmacology, 2009)
- Leonurine protects against tumor necrosis factor--mediated inflammation in human umbilical vein endothelial cells (Atherosclerosis, 2012)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCOC1=CC(=CC(=C1O)OC)C(=O)OCCCCN=C(N)N
-
InChIKeyWNGSUWLDMZFYNZ-UHFFFAOYSA-N
- Pubchem - Leonurine
- Wikipedia - leonurine
Leonurine is a pseudoalkaloid that has been isolated from Leonotis leonurus (Lion's tail), Leonotis nepetifolia, Leonotis artemisia, Leonurus cardiaca (Motherwort), Leonurus sibiricus, as well as other plants of family Lamiaceae. Leonurine is easily extracted into water.
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Synthesis
urea
+
Reactant
(Imine formation from aldehyde)
SYRINGIC ACID
+
Reactant
(Ester from carboxilic acid(SN2))
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