| Weight | 388.895 g/mol |
|---|---|
| Formula | C21H25ClN2O3 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 8 |
Levocetirizine (130018-77-8, 130018-87-0)
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- Levocetirizine improves quality of life and reduces costs in long-term management of persistent allergic rhinitis. (The Journal of Allergy and Clinical Immunology, 2004)
- The effectiveness of levocetirizine and desloratadine in up to 4 times conventional doses in difficult-to-treat urticaria. (The Journal of Allergy and Clinical Immunology, 2010)
- Binding characteristics of cetirizine and levocetirizine to human H1 histamine receptors: Contribution of Lys191 and Thr194 (Molecular Pharmacology, 2002)
- A randomized, doubleblind, crossover comparison among cetirizine, levocetirizine, and ucb 28557 on histamineinduced cutaneous responses in healthy adult volunteers (Allergy, 2001)
- A double-blind, randomized, single-dose, crossover comparison of levocetirizine with ebastine, fexofenadine, loratadine, mizolastine, and placebo: suppression of histamine-induced wheal-and-flare response during 24 hours in healthy male subjects. (Annals of Allergy Asthma & Immunology, 2002)
- Comparison of pharmacokinetics and metabolism of desloratadine, fexofenadine, levocetirizine and mizolastine in humans (Fundamental & Clinical Pharmacology, 2004)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1CN(CCN1CCOCC(=O)O)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl
-
InChIKeyZKLPARSLTMPFCP-UHFFFAOYSA-N
- Pubchem - Levocetirizine
- Wikipedia - levocetirizine
Levocetirizine (as levocetirizine dihydrochloride) is a third-generation, non-sedating antihistamine, developed from the second-generation antihistamine cetirizine. Chemically, levocetirizine is simply the isolated levorotary enantiomer of cetirizine, which is sold as a racemic mixture.
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Levocetirizine
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