| Weight | 309.453 g/mol |
|---|---|
| Formula | C21H27NO |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 7 |
Levomethadone (125-58-6)
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- Modulation of the central nervous effects of levomethadone by genetic polymorphisms potentially affecting its metabolism, distribution, and drug action (Clinical Pharmacology & Therapeutics, 2006)
- Anti-nociceptive Efficacy of Carprofen, Levomethadone and Buprenorphine for Pain Relief in Cats following Major Orthopaedic Surgery (Journal of Veterinary Medicine Series A-physiology Pathology Clinical Medicine, 2005)
- Analgesic effect of butorphanol and levomethadone in detomidine sedated horses. (Journal of Veterinary Medicine Series A-physiology Pathology Clinical Medicine, 2001)
- Side effects of levomethadone and racemic methadone in a maintenance program. (Clinical Pharmacology & Therapeutics, 1976)
- Pain perception of intravenous heroin users on maintenance therapy with levomethadone. (Pharmacopsychiatry, 1996)
- Contact heat thermal threshold testing in beagle dogs: baseline reproducibility and the effect of acepromazine, levomethadone and fenpipramide (BMC Veterinary Research, 2012)
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SMILESCCC(=O)C(CC(C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2
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- Pubchem - Levomethadone
- Wikipedia - levomethadone
Levomethadone (INN; L-Polamidon, L-Polamivet, Levadone, Levothyl), or levamethadone, is a synthetic opioid analgesic and antitussive which is marketed in Europe and is used for pain management and in opioid maintenance therapy. In addition to being used as a pharmaceutical drug itself, levomethadone, or R-()-methadone, is the active enantiomer of methadone, having approximately 50x the potency of the S-(+)-enantiomer as well as greater -opioid receptor selectivity. Accordingly, it is about twice as potent as methadone by weight and its effects are virtually identical in comparison.
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