| Weight | 359.474 g/mol |
|---|---|
| Formula | C19H29N5O2 |
| Hydrogen Acceptors | 7 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 9 |
Loxtidine (76956-02-0)
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SMILESCN1C(=NC(=N1)CO)NCCCOC2=CC=CC(=C2)CN3CCCCC3
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InChIKeyVTLNPNNUIJHJQB-UHFFFAOYSA-N
- Pubchem - Loxtidine
- Wikipedia - lavoltidine
Lavoltidine (INN, USAN, BAN; previously known as loxtidine, code name AH-23,844) is a highly potent and selective H2 receptor antagonist which was under development by Glaxo Wellcome (now GlaxoSmithKline) as a treatment for gastroesophageal reflux disease but was discontinued due to the discovery that it produced gastric carcinoid tumors in rodents.
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Synthesis
3-(1-Piperidinylmethyl)phenol
+
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