| Weight | 257.717 g/mol |
|---|---|
| Formula | C12H16ClNO3 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 6 |
meclofenoxate (51-68-3)
Centrophenoxine · Cetrexin · Helfergin
Score:
#1044 in Neuroscience
,
#2255 in Biochemistry
,
#4532 in Biology
,
#5747 in Chemistry
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- Effect of centrophenoxine on the lipofuscin pigments in the neurones of senile guinea-pigs. (Nature, 1966)
- Further studies on the effects of centrophenoxine on the lipofuscin pigment in the neurons of senile guinea pigs. (The Journals of Gerontology, 1968)
- Effects of centrophenoxine on the lipofuscin pigments in the nervous system of old rats (Brain Research, 1974)
- Centrophenoxine increases the rates of total and mRNA synthesis in the brain cortex of old rats: An explanation of its action in terms of the membrane hypothesis of aging (Experimental Gerontology, 1984)
- Alterations of the synaptosomal membrane microviscosity in the brain cortex of rats during aging and centrophenoxine treatment (Archives of Gerontology and Geriatrics, 1983)
- Effects of Centrophenoxine on the Monovalent Electrolyte Contents of the Large Brain Cortical Cells of Old Rats (Gerontology, 1979)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Centrophenoxine
- Cetrexin
- Helfergin
- Meclofenoxate Hydrochloride
- Atsefen
- Cerutil
-
SMILESCN(C)CCOC(=O)COC1=CC=C(C=C1)Cl
-
InChIKeyXZTYGFHCIAKPGJ-UHFFFAOYSA-N
- Pubchem - meclofenoxate
- Wikipedia - meclofenoxate
Meclofenoxate (INN, BAN) (brand name Lucidril), also known as centrophenoxine, is a cholinergic nootropic used as a dietary supplement and drug in the treatment of symptoms of senile dementia and Alzheimer's disease. It is an ester of dimethylethanolamine (DMAE) and 4-chlorophenoxyacetic acid (pCPA). In elderly patients, meclofenoxate has been found clinically to improve memory, have a mentally stimulating effect, and improve general cognition.
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Synthesis
4-CHLOROPHENOL
+
Reactant
(Williamson ether)
Reactant
+
dimethyl sulfide
(Corey-Kim oxidation of secondary alcohols)
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