| Weight | 182.219 g/mol |
|---|---|
| Formula | C10H14O3 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 4 |
mephenesin (59-47-2)
Dcontractyl · Dolo Visano M
Score:
#956 in Neuroscience
,
#4181 in Biology
,
#5269 in Chemistry
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- SITE OF ACTION OF MYANESIN (MEPHENESIN, TOLSEROL) IN THE CENTRAL NERVOUS SYSTEM (Journal of Neurophysiology, 1950)
- THE ACTION OF MEPHENESIN AND OTHER INTERNEURON DEPRESSANTS ON THE BRAIN STEM (Journal of Pharmacology and Experimental Therapeutics, 1954)
- The action of mephenesin and other agents on the effects produced by two neurotoxic pyrethroids in the intact and spinal rat (Neuropharmacology, 1983)
- Kinetic resolution of rac-3-(2-methylphenoxy)propane-1,2-diol (mephenesin) by sequential lipase-catalyzed transesterification (Tetrahedron-asymmetry, 1991)
- THE CORRELATION BETWEEN ANIMAL TESTING PROCEDURES AND CLINICAL EFFECTIVENESS OF CENTRALLY ACTING MUSCLE RELAXANTS OF THE MEPHENESIN TYPE (Annals of the New York Academy of Sciences, 1956)
- LFFLER'S SYNDROME: REPORT OF A CASE ASSOCIATED WITH ADMINISTRATION OF MEPHENESIN CARBAMATE (TOLSERAM) (Annals of Internal Medicine, 1958)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Dcontractyl
- Dolo Visano M
-
SMILESCC1=CC=CC=C1OCC(CO)O
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InChIKeyJWDYCNIAQWPBHD-UHFFFAOYSA-N
- Pubchem - mephenesin
- Wikipedia - mephenesin
Mephenesin is a centrally acting muscle relaxant. It can be used as an antidote for strychnine poisoning. Mephenesin however presents with the major drawbacks of having a short duration of action and a much greater effect on the spinal cord than the brain, resulting in pronounced respiratory depression at clinical doses and therefore a very low therapeutic index.
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