| Weight | 309.453 g/mol |
|---|---|
| Formula | C21H27NO |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 7 |
methadone (76-99-3)
Dolophine · Methadone Hydrochloride · Amidone
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- Buprenorphine maintenance versus placebo or methadone maintenance for opioid dependence (Cochrane Database of Systematic Reviews, 2003)
- The Effectiveness of Methadone Maintenance Treatment (1991)
- A Medical Treatment for Diacetylmorphine (Heroin) Addiction: A Clinical Trial With Methadone Hydrochloride (JAMA, 1965)
- Methadone maintenance therapy versus no opioid replacement therapy for opioid dependence (Cochrane Database of Systematic Reviews, 2009)
- A comparison of levomethadyl acetate, buprenorphine, and methadone for opioid dependence. (The New England Journal of Medicine, 2000)
- Opioids and the Management of Chronic Severe Pain in the Elderly: Consensus Statement of an International Expert Panel with Focus on the Six Clinically Most Often Used World Health Organization step III Opioids (Buprenorphine, Fentanyl, Hydromorphone, Methadone, Morphine, Oxycodone) (Pain Practice, 2008)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Dolophine
- Methadone Hydrochloride
- Amidone
- Methadose
- Physeptone
- Methex
- Metasedin
- Biodone
- Pinadone
- Phymet
- Methaddict
- Symoron
- Metadol
- Phenadone
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SMILESCCC(=O)C(CC(C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2
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InChIKeyUSSIQXCVUWKGNF-UHFFFAOYSA-N
- Pubchem - methadone
- Wikipedia - methadone
Methadone, sold under the brand name Dolophine, among others, is an opioid used to treat pain and as maintenance therapy or to help with tapering in people with opioid dependence. Detoxification using methadone can either be done relatively rapidly in less than a month or gradually over as long as six months. While a single dose has a rapid effect, maximum effect can take five days of use.
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Estimated Properties
| Boiling Point | 354.07 C | EPA T.E.S.T. |
|---|---|---|
| Density | 0.99 g/cm3 | EPA T.E.S.T. |
| Flash Point | 162.23 C | EPA T.E.S.T. |
| Water Solubility | 17.44 mg/L | EPA T.E.S.T. |
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methadone
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