| Weight | 183.207 g/mol |
|---|---|
| Formula | C9H13NO3 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 4 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 2 |
Methylnoradrenaline
Levonordefrin · Methylnorepinephrine · Nordefrin
829-74-3, 6539-57-7, 74812-63-8
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- Release by sympathetic stimulation of -methylnoradrenaline stored in the heart after administration of -methyldopa (Cellular and Molecular Life Sciences, 1963)
- Inhibition of neuronal uptake reduces the presynaptic effects of clonidine but not of -methylnoradrenaline on the stimulation-evoked release of 3H-noradrenaline from rat occipital cortex slices (European Journal of Pharmacology, 1980)
- Centrally induced hypotension and bradycardia after administration of alpha-methylnoradrenaline into the area of the nucleus tractus solitarii of the rat. (British Journal of Pharmacology, 1976)
- Evidence that the hypotensive action of methyldopa is mediated by central actions of methylnoradrenaline (Journal of Pharmacy and Pharmacology, 1971)
- Anesthetic efficacy and heart rate effects of the supplemental intraosseous injection of 2% mepivacaine with 1:20,000 levonordefrin (Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology, 1999)
- Failure of Reserpine to Deplete Noradrenaline Neurons of Methylnoradrenaline Formed from Methyl DOPA (Pharmacology & Toxicology, 2009)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Levonordefrin
- Methylnorepinephrine
- Nordefrin
- Cobefrine
- 4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol
- Neo-Cobefrin
- 4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol, (R*,S*)-Isomer
- alpha-Methylnoradrenaline
- Nordefrin, (R*,S*)-Isomer
- Nordefrin, (R*,R*)-Isomer
- 4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol Hydrochloride, (R*,S*)-(+-)-Isomer
- Norephrine
- 4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol Tartrate, (R*,R*), (R*,R*)-Isomer
- Nordefrin Tartrate, (R*,S*), (R*,R*) Isomer
- Nordefrin Hydrochloride
- alpha-Methylnorepinephrine
- 4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol Tartrate, (R*,S*), (R*,R*)-Isomer
- Nordefrin Hydrochloride, (R*,S*)-(+,-)-Isomer
- 3,4 Dihydroxynorephedrine
- Nordefrin Hydrochloride, (R*,R*)-(+,-)-Isomer
- 4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol Hydrochloride, (R*,R*)-(+,-)-Isomer
- 4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol, (R*,R*)-Isomer
- 3,4-Dihydroxynorephedrine
- alpha Methylnoradrenaline
- NeoCobefrin
- Neo Cobefrin
- alpha Methylnorepinephrine
- Nordefrin Tartrate, (R*,R*), (R*,R*) Isomer
- Corbadrine
-
SMILESCC(C(C1=CC(=C(C=C1)O)O)O)N
-
InChIKeyGEFQWZLICWMTKF-UHFFFAOYSA-N
- Pubchem - Methylnoradrenaline
- Wikipedia - -methylnoradrenaline
Corbadrine (INN; marketed as Neo-Cobefrine), also known as levonordefrin (USAN) and -methylnorepinephrine, is a catecholamine sympathomimetic used as a topical nasal decongestant and vasoconstrictor in dentistry in the United States, (usually in a pre-mixed solution with local anesthetics, such as mepivacaine). Corbadrine is also a metabolite of the antihypertensive drug methyldopa, and plays a role in its pharmacology and effects.
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