| Weight | 445.61 g/mol |
|---|---|
| Formula | C22H27N3O3S2 |
| Hydrogen Acceptors | 6 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 6 |
Metopimazine (14008-44-7)
metopimazine hydrochloride · 1-(3-(2-methylsulfonylphenothiazin-10-yl) propyl)isonipecotinamide · Vogalene
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- Ondansetron plus Metopimazine Compared with Ondansetron Alone in Patients Receiving Moderately Emetogenic Chemotherapy (The New England Journal of Medicine, 1993)
- Ondansetron Plus Metopimazine Compared With Ondansetron Plus Metopimazine Plus Prednisolone as Antiemetic Prophylaxis in Patients Receiving Multiple Cycles of Moderately Emetogenic Chemotherapy (Journal of Clinical Oncology, 2001)
- Evidence of lowest brain penetration of an antiemetic drug, metopimazine, compared to domperidone, metoclopramide and chlorpromazine, using an in vitro model of the blood-brain barrier. (Pharmacological Research, 2007)
- Controlled studies of metopimazine for the treatment of nausea and vomiting. (The journal of clinical pharmacology and new drugs, 1973)
- Effect of iontophoresis and penetration enhancers on transdermal absorption of metopimazine (Journal of Dermatological Science, 2008)
- The efficacy of a combination of ondansetron, methyiprednisolone and metopimazine in patients previously uncontrolled with a dual antiemetic treatment in cisplatin-based chemotherapy (Annals of Oncology, 1997)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - metopimazine hydrochloride
- 1-(3-(2-methylsulfonylphenothiazin-10-yl) propyl)isonipecotinamide
- Vogalene
-
SMILESCS(=O)(=O)C1=CC2=C(C=C1)SC3=CC=CC=C3N2CCCN4CCC(CC4)C(=O)N
-
InChIKeyBQDBKDMTIJBJLA-UHFFFAOYSA-N
- Pubchem - Metopimazine
- Wikipedia - metopimazine
Metopimazine (INN) is a phenothiazine antiemetic.
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