| Weight | 226.279 g/mol |
|---|---|
| Formula | C14H14N2O |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 3 |
metyrapone (54-36-4)
Metopirone · SU 4885 · Methopyrapone
Score:
#435 in Neuroscience
,
#718 in Biochemistry
,
#1995 in Biology
,
#2431 in Chemistry
"What do you need help with?"
LabBot
- Sigma-Aldrich - metyrapone21.80 - 338.10 USD
- Fisher Scientific - Search for metyrapone
- TCI - Search for metyrapone
- Crystal Structures of Human Cytochrome P450 3A4 Bound to Metyrapone and Progesterone (Science, 2004)
- SHORT AND LONG-TERM RESPONSES TO METYRAPONE IN THE MEDICAL MANAGEMENT OF 91 PATIENTS WITH CUSHING'S SYNDROME (Clinical Endocrinology, 1991)
- Crystal structures of metyrapone- and phenylimidazole-inhibited complexes of cytochrome P-450cam. (Biochemistry, 1987)
- Metyrapone, an Inhibitor of Glucocorticoid Production, Reduces Brain Injury Induced by Focal and Global Ischemia and Seizures (Journal of Cerebral Blood Flow and Metabolism, 1996)
- Dose-dependent suppression of adrenocortical activity with metyrapone: Effects on emotion and memory (Psychoneuroendocrinology, 1996)
- Central serotonergic responses and behavioural adaptation to repeated immobilisation: The effect of the corticosterone synthesis inhibitor metyrapone (European Journal of Pharmacology, 1985)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Metopirone
- SU 4885
- Methopyrapone
- Metopiron
- Metyrapone Alliance Brand
- Methbipyranone
- Alliance Brand of Metyrapone
- Novartis Brand of Metyrapone
- Mtopirone
- Metyrapone Novartis Brand
-
SMILESCC(C)(C1=CN=CC=C1)C(=O)C2=CN=CC=C2
-
InChIKeyFJLBFSROUSIWMA-UHFFFAOYSA-N
- Pubchem - metyrapone
- Wikipedia - metyrapone
Metyrapone (trade name Metopirone) is a drug used in the diagnosis of adrenal insufficiency and occasionally in the treatment of Cushing's syndrome (hypercortisolism).
Suppliers
Most-cited Publications
Areas of Application
Safety
Trends
Alternate Names
External Links
Synthesis
Pyridine
+
Reactant
(Friedel-Crafts alkylation)
Reactant
+
3-CHLOROPYRIDINE
(Grignard carbonyl)
Similar Compounds
2-methyl-1-(pyridin-3-yl)propan-1-one
(51227-29-3)
11 alternate names
3 suppliers
cyclopropyl(3-pyridinyl)methanone
(24966-13-0)
11 alternate names
3 suppliers
3-Propionylpyridine
(1570-48-5)
11 alternate names
3 suppliers
1-(Pyridin-3-yl)pentan-1-one
(1701-72-0)
11 alternate names
3 suppliers
3-Methyl-1-(3-pyridyl)-1-butanone
(82465-52-9)
11 alternate names
3 suppliers
1-(Pyridin-3-yl)butane-1,3-dione
(3594-37-4)
11 alternate names
3 suppliers
3-succinoylpyridine
(4192-31-8)
11 alternate names
3 suppliers
Methyl nicotinoylacetate
(54950-20-8)
11 alternate names
3 suppliers
582-73-0
(582-73-0)
11 alternate names
3 suppliers
6283-81-4
(6283-81-4)
11 alternate names
3 suppliers
394655-14-2
(394655-14-2)
11 alternate names
3 suppliers
Piperidin-3-yl(pyridin-3-yl)methanone
(1221278-60-9)
11 alternate names
3 suppliers
piperidin-3-yl(pyridin-3-yl)methanone dihydrochloride
(1301738-69-1)
11 alternate names
3 suppliers
2-Oxo-2-(pyridin-3-yl)acetic acid
(39684-37-2)
11 alternate names
3 suppliers
oxo(3-pyridinyl)acetic acid hydrate
(1559061-98-1)
11 alternate names
3 suppliers
3-ACETYLPYRIDINE
(350-03-8)
11 alternate names
3 suppliers
1,2,4-Triphenyl-1,4-butanedione
(4441-01-4)
11 alternate names
3 suppliers
17694-68-7
(17694-68-7)
11 alternate names
3 suppliers
1-(1H-indol-3-yl)-2-methyl-1-propanone
(57642-07-6)
11 alternate names
3 suppliers
cyclopropyl(1H-indol-3-yl)methanone
(675834-79-4)
11 alternate names
3 suppliers
2-(4-methylphenyl)-1H-indene-1,3(2H)-dione
(7561-48-0)
11 alternate names
3 suppliers
2-(2-methylphenyl)-1H-indene-1,3(2H)-dione
(60338-36-5)
11 alternate names
3 suppliers
1,10-Phenanthroline-5,6-dione
(27318-90-7)
11 alternate names
3 suppliers
(1,3-dioxo-2-phenyl-2,3-dihydro-1H-inden-2-yl)acetic acid
(7443-02-9)
11 alternate names
3 suppliers
3-ACETYL-5-BROMOPYRIDINE
(38940-62-4)
11 alternate names
3 suppliers
5-Acetyl-2-methylpyridine
(36357-38-7)
11 alternate names
3 suppliers
2,3-di(3-Pyridyl)-2,3-butanediol
(4989-59-7)
11 alternate names
3 suppliers
1-(3-pyridinyl)acetone hydrochloride
(69966-56-9)
11 alternate names
3 suppliers
1-pyridin-3-ylacetone
(6302-03-0)
11 alternate names
3 suppliers
3-Acetylpyridine N-oxide
(14188-94-4)
11 alternate names
3 suppliers
28566-14-5
(28566-14-5)
11 alternate names
3 suppliers
1-(1H-Indol-3-yl)butan-1-one
(22582-67-8)
11 alternate names
3 suppliers
3-(1H-indol-3-yl)-3-oxopropanenitrile
(20356-45-0)
11 alternate names
3 suppliers
1-(1H-Indol-3-yl)propan-1-one
(22582-68-9)
11 alternate names
3 suppliers
Indole-3-(4'-oxo)butyric acid
(835-45-0)
11 alternate names
3 suppliers
2-(3,4-Dimethoxyphenyl)-1H-indene-1,3(2H)-dione
(1470-38-8)
11 alternate names
3 suppliers
6266-66-6
(6266-66-6)
11 alternate names
3 suppliers
3-acetyl-2(1H)-pyridinone
(62838-65-7)
11 alternate names
3 suppliers
1-Phenyl-2-(pyridin-4-yl)ethanone
(1620-55-9)
11 alternate names
3 suppliers
3-Acetyl-2-chloropyridine
(55676-21-6)
11 alternate names
3 suppliers
3-Dimethylamino-1-(3-pyridyl)-2-propen-1-one
(123367-26-0)
11 alternate names
3 suppliers
cis-3-(3-pyridinyl)cyclobutanamine dihydrochloride
(2089291-85-8, 2089292-20-4, 1909308-44-6)
11 alternate names
3 suppliers
1-(2,6-DICHLOROPYRIDIN-3-YL)ETHANONE
(412018-50-9)
11 alternate names
3 suppliers
(3-Cyclopropanecarbonyl-indol-1-yl)-acetic acid
(708295-12-9)
11 alternate names
3 suppliers
15450-69-8
(15450-69-8)
11 alternate names
3 suppliers
1801-20-3
(1801-20-3)
11 alternate names
3 suppliers
3-nonan-5-ylpyridine
(2961-48-0)
11 alternate names
3 suppliers
7,7-dimethyl-7,8-dihydro-2,5(1H,6H)-quinolinedione
(55119-00-1)
11 alternate names
3 suppliers
5-(pyridin-3-yl)-pentanoic acid
(36599-14-1)
11 alternate names
3 suppliers
124467-36-3
(124467-36-3)
11 alternate names
3 suppliers
methyl 4-(1H-indol-3-yl)-2,4-dioxobutanoate
(718603-58-8)
11 alternate names
3 suppliers
1-(indolizin-2-yl)ethanone
(58475-97-1)
11 alternate names
3 suppliers
1-phenyl-2-pyrazin-2-ylethanone
(40061-45-8)
11 alternate names
3 suppliers
2-bromo-2-(4-chlorophenyl)-1H-indene-1,3(2H)-dione
(730-73-4)
11 alternate names
3 suppliers
3-Indoleglyoxylic acid
(1477-49-2)
11 alternate names
3 suppliers
3-(3-Chloropropyl)pyridine hydrochloride
(17944-58-0)
11 alternate names
3 suppliers
3-(3-Pyridyl)propionic acid
(3724-19-4)
11 alternate names
3 suppliers
3-pyridineacetic acid
(6419-36-9, 501-81-5)
11 alternate names
3 suppliers
3-Pyridylacetic acid hydrochloride
(6419-36-9)
11 alternate names
3 suppliers
(3-Butyryl-1H-indol-1-yl)acetic acid
(892676-98-1)
11 alternate names
3 suppliers
3-(2-methyl-1h-indol-3-yl)-3-oxopropanenitrile
(76397-72-3)
11 alternate names
3 suppliers
2-(pyridin-3-yl)acetamide
(3724-16-1)
11 alternate names
3 suppliers
Methyl 3-indoleglyoxylate
(18372-22-0)
11 alternate names
3 suppliers
3-(piperidin-4-ylmethyl)pyridine
(148148-60-1)
11 alternate names
3 suppliers
2,3-Dimethyl-2,3-diphenylbutane
(1889-67-4)
11 alternate names
3 suppliers
3-(3-Bromopropyl)pyridine hydrobromide
(41038-63-5)
11 alternate names
3 suppliers
51079-10-8
(51079-10-8)
11 alternate names
3 suppliers
3-(3-pyridinyl)-1-propanamine
(41038-69-1)
11 alternate names
3 suppliers
26138-64-7
(26138-64-7)
11 alternate names
3 suppliers
2-Methyl-1-(3-pyridinyl)-1-propanamine dihydrochloride
(72954-99-5)
11 alternate names
3 suppliers
1,5,6,7-Tetrahydro-4H-indol-4-one
(13754-86-4)
11 alternate names
3 suppliers
Ramosetron hydrochloride
(132907-72-3)
11 alternate names
3 suppliers
4-(2-PYRIDINYLACETYL)BENZOIC ACID
(915920-55-7)
11 alternate names
3 suppliers
3-Acetylindole
(703-80-0)
11 alternate names
3 suppliers
3-Pyridinepropanethiol
(69603-49-2)
11 alternate names
3 suppliers
75238-44-7
(75238-44-7)
11 alternate names
3 suppliers
28755-03-5
(28755-03-5)
11 alternate names
3 suppliers
2-chloro-1-(5-methoxy-1H-indol-3-yl)ethanone
(30030-91-2)
11 alternate names
3 suppliers
1-(pyridin-3-yl)propan-2-amine
(71271-61-9)
11 alternate names
3 suppliers
(2s)-3-(4-hydroxyphenyl)-2-phenylpropanoic acid
(89-23-6)
11 alternate names
3 suppliers
3-Pyridinepropanol
(2859-67-8)
11 alternate names
3 suppliers
2,5-dioxo-1,2,5,6,7,8-hexahydro-3-quinolinecarboxylic acid
(106551-76-2)
11 alternate names
3 suppliers
39998-25-9
(39998-25-9)
11 alternate names
3 suppliers
p-Cumenyl cyclopropyl ketone
(6952-91-6)
11 alternate names
3 suppliers
4-oxo-2,4-diphenylbutanoic acid
(4370-96-1)
11 alternate names
3 suppliers
piperidin-4-yl(pyridin-3-yl)methanol
(884504-88-5)
11 alternate names
3 suppliers
2-Hydroxy-1-(1H-indol-3-yl)ethanone
(2400-51-3)
11 alternate names
3 suppliers
4-(3-pyridinyl)-4-piperidinol dihydrochloride hydrate
11 alternate names
3 suppliers
4-(pyridin-3-yl)piperidin-4-ol
(50461-59-1)
11 alternate names
3 suppliers
Iodoalphionic acid
(7009-60-1, 577-91-3)
11 alternate names
3 suppliers
2,2,2-trichloro-1-(1H-indol-3-yl)ethanone
(30030-90-1)
11 alternate names
3 suppliers
6,7-Dihydro-5H-cyclopenta[b]pyridine-3-carboxylic acid
(114402-11-8)
11 alternate names
3 suppliers
Pyridine, 3-(3-butenyl)-
(71532-24-6)
11 alternate names
3 suppliers
4-oxo-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid
(3123-46-4)
11 alternate names
3 suppliers
5,6,7,8-Tetrahydroquinoline-3-carboxylic acid
(82345-76-4)
11 alternate names
3 suppliers
2-(5-bromo-3-pyridinyl)-2-propanol hydrochloride
(1609403-17-9)
11 alternate names
3 suppliers
1-(3-pyridinyl)-1-propanamine
(60289-67-0)
11 alternate names
3 suppliers
metyrapone
CAS Directory
