| Weight | 387.911 g/mol |
|---|---|
| Formula | C21H26ClN3O2 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 6 |
nemonapride (75272-39-8)
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- The relationship between dopamine D2 receptor polymorphism at the Taq1 A locus and therapeutic response to nemonapride, a selective dopamine antagonist, in schizophrenic patients (Pharmacogenetics, 2000)
- 5-HT1A receptor agonist properties of the antipsychotic, nemonapride: comparison with bromerguride and clozapine (European Journal of Pharmacology, 1997)
- Schizophrenia: elevation of dopamine D4-like sites, using [3H]nemonapride and [125I]epidepride (European Journal of Pharmacology, 1995)
- Prolactin response to nemonapride, a selective antagonist for D2 like dopamine receptors, in schizophrenic patients in relation to Taq1A polymorphism of DRD2 gene. (Psychopharmacology, 2000)
- Dopamine D4-like receptor elevation in schizophrenia: cloned D2 and D4 receptors cannot be discriminated by raclopride competition against [^3H]nemonapride (Journal of Neurochemistry, 2002)
- No relationship between Taq1 a polymorphism of dopamine D2 receptor gene and extrapyramidal adverse effects of selective dopamine D2 antagonists, bromperidol, and nemonapride in schizophrenia: A preliminary study (American Journal of Medical Genetics, 2000)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC1C(CCN1CC2=CC=CC=C2)NC(=O)C3=CC(=C(C=C3OC)NC)Cl
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InChIKeyKRVOJOCLBAAKSJ-UHFFFAOYSA-N
- Pubchem - nemonapride
- Wikipedia - nemonapride
Nemonapride (, Emilace (JP)) is an atypical antipsychotic approved in Japan for the treatment of schizophrenia. It was launched by Yamanouchi in 1991. Nemonapride acts as a D2 and D3 receptor antagonist, and is also a potent 5-HT1A receptor agonist.
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