Weight | 223.296 g/mol |
---|---|
Formula | C12H19N2O2+ |
Hydrogen Acceptors | 2 |
Hydrogen Donors | 0 |
Aromatic Rings | 1 |
Rotatable Bonds | 2 |
NEOSTIGMINE (59-99-4)
Prostigmin · Prostigmine · Neostigmine Methylsulfate
Score:
#441 in Neuroscience
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#2025 in Biology
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#2473 in Chemistry
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- THE INHIBITION OF CHOLINESTERASE BY PHYSOSTIGMINE AND PROSTIGMINE (Journal of Biological Chemistry, 1942)
- Neostigmine for the treatment of acute colonic pseudo-obstruction. (The New England Journal of Medicine, 1999)
- Letter: Experimental myopathy induced by neostigmine methylsulphate. (The Lancet, 1975)
- Phase I safety assessment of intrathecal neostigmine methylsulfate in humans (Anesthesiology, 1995)
- Reversal of profound rocuronium-induced blockade with sugammadex: a randomized comparison with neostigmine. (Anesthesiology, 2008)
- Microinjection of neostigmine into the pontine reticular formation of cats enhances desynchronized sleep signs. (Journal of Pharmacology and Experimental Therapeutics, 1984)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Prostigmin
- Prostigmine
- Neostigmine Methylsulfate
- Neostigmine Bromide
- Syntostigmine
- Synstigmin
- Proserine
- Polstigmine
- Prozerin
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SMILESCN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C
-
InChIKeyALWKGYPQUAPLQC-UHFFFAOYSA-N
- Pubchem - NEOSTIGMINE
- Wikipedia - neostigmine
Neostigmine, sold under the brand name Prostigmin among others, is a medication used to treat myasthenia gravis, Ogilvie syndrome, and urinary retention without the presence of a blockage. It is also used together with atropine to end the effects of neuromuscular blocking medication of the non-depolarizing type. It is given by injection either into a vein, muscle, or under the skin.
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