| Weight | 317.223 g/mol |
|---|---|
| Formula | C12H10F3N3O4 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 2 |
nilutamide (63612-50-0)
Nilandron · Anandron · RU 23908
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- Prevention of the transient adverse effects of a gonadotropin-releasing hormone analogue (buserelin) in metastatic prostatic carcinoma by administration of an antiandrogen (nilutamide). (The New England Journal of Medicine, 1989)
- Orchiectomy and Nilutamide or Placebo as Treatment of Metastatic Prostatic Cancer in a Multinational Double-Blind Randomized Trial (The Journal of Urology, 1993)
- Long-term efficacy and safety of nilutamide plus castration in advanced prostate cancer, and the significance of early prostate specific antigen normalization (The Journal of Urology, 1997)
- Analysis of Overall Survival in Patients with Nonmetastatic Castration-Resistant Prostate Cancer Treated with Vaccine, Nilutamide, and Combination Therapy (Clinical Cancer Research, 2008)
- Nilutamide as Second Line Hormone Therapy for Prostate Cancer After Androgen Ablation Fails (The Journal of Urology, 2003)
- Monotherapy with Nilutamide, A Pure Nonsteroidal Antiandrogen, in Untreated Patients with Metastatic Carcinoma of the Prostate (The Journal of Urology, 1991)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Nilandron
- Anandron
- RU 23908
- Aventis Brand of Nilutamide
- Aventis Behring Brand of Nilutamide
- RU 23908-10
- RU-23908
- 5,5-dimethyl-3-(4-nitro-3-(trifluoromethyl)phenyl)- 2,4-imidazolidinedione
- Hoechst Brand of Nilutamide
-
SMILESCC1(C(=O)N(C(=O)N1)C2=CC(=C(C=C2)[N+](=O)[O-])C(F)(F)F)C
-
InChIKeyXWXYUMMDTVBTOU-UHFFFAOYSA-N
- Pubchem - nilutamide
- Wikipedia - nilutamide
Nilutamide, sold under the brand names Nilandron and Anandron, is a nonsteroidal antiandrogen (NSAA) which is used in the treatment of prostate cancer. It has also been studied as a component of feminizing hormone therapy for transgender women and to treat acne and seborrhea in women. It is taken by mouth.
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Reactant
+
CID 18409438
(Schotten-Baumann amide from acid)
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nilutamide
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