NITAZOXANIDE (55981-09-4)

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Suppliers

• Sigma-Aldrich - NITAZOXANIDE
  61.80 - 338.10 USD
• Fisher Scientific - Search for NITAZOXANIDE
• TCI - Search for NITAZOXANIDE

Most-cited Publications

• Treatment of Diarrhea Caused by Cryptosporidium parvum: A Prospective Randomized, Double-Blind, Placebo-Controlled Study of Nitazoxanide (The Journal of Infectious Diseases, 2001)
• Nitazoxanide: A New Thiazolide Antiparasitic Agent (Clinical Infectious Diseases, 2005)
• Effect of nitazoxanide on morbidity and mortality in Zambian children with cryptosporidiosis: a randomised controlled trial (The Lancet, 2002)
• Nitazoxanide for the Treatment of Clostridium difficile Colitis (Clinical Infectious Diseases, 2006)
• Nitazoxanide, tizoxanide and other thiazolides are potent inhibitors of hepatitis B virus and hepatitis C virus replication. (Antiviral Research, 2008)
• In vitro activity of nitazoxanide and related compounds against isolates of Giardia intestinalis, Entamoeba histolytica and Trichomonas vaginalis (Journal of Antimicrobial Chemotherapy, 2002)

Areas of Application

Safety

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Trends

Alternate Names

• NTZ
• Daxon
• Alinia
• Heliton
• Columbia Brand 2 of Nitazoxanide
• Columbia Brand 3 of Nitazoxanide
• Cryptaz
• Columbia Brand 1 of Nitazoxanide
• Colufase
• Romark Brand 2 of Nitazoxanide
• Romark Brand 1 of Nitazoxanide
• Taenitaz
• SMILES
  CC(=O)OC1=CC=CC=C1C(=O)NC2=NC=C(S2)[N+](=O)[O-]
• InChIKey
  YQNQNVDNTFHQSW-UHFFFAOYSA-N

External Links

• Pubchem - NITAZOXANIDE
• Wikipedia - nitazoxanide
  Nitazoxanide is a broad-spectrum antiparasitic and broad-spectrum antiviral drug that is used in medicine for the treatment of various helminthic, protozoal, and viral infections. It is indicated for the treatment of infection by Cryptosporidium parvum and Giardia lamblia in immunocompetent individuals and has been repurposed for the treatment of influenza. Nitazoxanide has also been shown to have in vitro antiparasitic activity and clinical treatment efficacy for infections caused by other protozoa and helminths; emerging evidence suggests that it possesses efficacy in treating a number of viral infections as well.

Synthesis

2-Acetoxybenzoyl chloride  +  2-AMINO-5-NITROTHIAZOLE (Schotten-Baumann amide from acid)

Synthesis of NITAZOXANIDE ›

Similar Compounds

Tizoxanide (173903-47-4)

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TENONITROZOLE (3810-35-3)

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4-hydroxy-N-1,3-thiazol-2-ylbenzamide (94042-62-3)

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35245-26-2 (35245-26-2)

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Nithiamide (140-40-9)

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255874-78-3 (255874-78-3)

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4-bromo-N-(4-methyl-1,3-thiazol-2-yl)benzamide (302967-87-9)

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2-amino-N-1,3-thiazol-2-ylbenzamide (33373-89-6)

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2-ethoxy-N-(4-iodophenyl)benzamide (312588-69-5)

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36855-80-8 (36855-80-8)

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3-amino-2-methyl-N-1,3-thiazol-2-ylbenzamide (402585-79-9)

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N-(4-Thiophen-2-yl-thiazol-2-yl)-phthalamic acid (325807-37-2)

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N-(2-bromo-4-methylphenyl)-2-ethoxybenzamide (314022-94-1)

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N-benzyl-6-methoxy-1,3-benzothiazol-2-amine (16763-01-2)

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N-(2-bromophenyl)-5-chloro-2-methoxybenzamide (349538-99-4)

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2-(Diethylamino)ethyl 4-(2-(octyloxy)benzamido)benzoate (26090-29-9)

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2-[2-(4-bromophenyl)-2-oxoethoxy]benzamide (337925-74-3)

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Flt-3 inhibitor (301305-73-7)

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(ortho-carbamoylphenoxy)acetic acid (25395-22-6)

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thiostrepton (1393-48-2)

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16673-34-0 (16673-34-0)

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sultopride hydrochloride (23694-17-9, 55619-22-2)

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N-(3-Aminophenyl)-2-methoxybenzamide (301207-46-5)

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N-(2-bromo-4-methylphenyl)-2-methoxybenzamide (353784-16-4)

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Foropafant (136468-36-5)

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{2-[(diisopropylamino)carbonyl]-3-methoxyphenyl}boronic acid (129112-20-5)

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Bleomycin sulfate (11056-06-7, 9041-93-4)

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5-Hydroxy-2-(2-methoxyethoxy)benzamide (28173-87-7)

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5-Bromo-2-ethoxybenzamide (54924-78-6)

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2-(5-methyl-1,3,4-thiadiazol-2-yl)-1,3-dioxoisoindoline-5-carboxylic acid (384795-95-3)

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azasetron hydrochloride (123040-16-4, 123040-69-7)

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2-ETHOXYBENZAMIDE (938-73-8)

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301694-50-8 (301694-50-8)

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31188-91-7 (31188-91-7)

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UNII-U3L0HCE5OI (6885-57-0)

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sulforhodamine 101 (60311-02-6)

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Aflatoxin B1 (1162-65-8)

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57645-91-7 (57645-91-7)

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2-Ethoxybenzhydrazide (21018-13-3)

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vitamin B12 (13408-78-1, 68-19-9)

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ATORVASTATIN CALCIUM (110862-48-1, 134523-03-8)

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3-[(dimethylamino)carbonyl]-4-methoxybenzenesulfonyl chloride (1114594-34-1)

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2-(4-formylphenoxy)-N-1,3-thiazol-2-ylacetamide (215503-93-8)

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IRINOTECAN HYDROCHLORIDE Trihydrate (136572-09-3)

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1-(2,6-dimethoxybenzoyl)piperidine-4-carboxylic acid (593261-82-6)

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6637-15-6 (6637-15-6)

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126643-37-6 (126643-37-6)

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1-[3-(6-bromo-2H-1,3-benzoxazin-3(4H)-yl)phenyl]ethanone (374911-94-1)

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3158-91-6 (3158-91-6)

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2-octoxybenzohydrazide Hydrochloride (27830-17-7)

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Closantel (57808-65-8)

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AFLATOXIN G2 (7241-98-7)

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(2-Methoxy-phenyl)-piperazin-1-yl-methanone trifluoroacetate (436099-85-3)

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Mollicellin D (68455-11-8)

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61354-99-2 (61354-99-2)

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vineomycin a1 (78164-00-8)

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137-52-0 (137-52-0)

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2,3-Dimethoxybenzamide (1521-39-7)

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Etoxazole (153233-91-1)

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penitrem A (12627-35-9)

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NITAZOXANIDE

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