| Weight | 301.327 g/mol |
|---|---|
| Formula | C14H11N3O3S |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 3 |
nocodazole (31430-18-9)
NSC238159 · R-17934 · R 17934
Score:
#42 in Molecular and cellular biology
,
#1311 in Biochemistry
,
#3208 in Biology
,
#4013 in Chemistry
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- Sigma-Aldrich - nocodazole27.10 - 353.00 USD
- Fisher Scientific - Search for nocodazole
- TCI - Search for nocodazole
- Effects of vinblastine, podophyllotoxin and nocodazole on mitotic spindles. Implications for the role of microtubule dynamics in mitosis. (Journal of Cell Science, 1992)
- The effects of methyl (5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl) carbamate, (R 17934; NSC 238159), a new synthetic antitumoral drug interfering with microtubules, on mammalian cells cultured in vitro. (Cancer Research, 1976)
- Nanomolar concentrations of nocodazole alter microtubule dynamic instability in vivo and in vitro. (Molecular Biology of the Cell, 1997)
- Recycling of Golgi-resident Glycosyltransferases through the ER Reveals a Novel Pathway and Provides an Explanation for Nocodazole-induced Golgi Scattering (Journal of Cell Biology, 1998)
- Production of large numbers of mitotic mammalian cells by use of the reversible microtubule inhibitor nocodazole. Nocodazole accumulated mitotic cells. (Experimental Cell Research, 1980)
- Interaction of oncodazole (R 17934), a new anti-tumoral drug, with rat brain tubulin (Biochemical and Biophysical Research Communications, 1976)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - NSC238159
- R-17934
- R 17934
- Oncodazole
- NSC 238159
- NSC-238159
- R17934
-
SMILESCOC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C3=CC=CS3
-
InChIKeyKYRVNWMVYQXFEU-UHFFFAOYSA-N
- Pubchem - nocodazole
- Wikipedia - nocodazole
Nocodazole is an antineoplastic agent which exerts its effect in cells by interfering with the polymerization of microtubules. Microtubules are one type of fibre which constitutes the cytoskeleton, and the dynamic microtubule network has several important roles in the cell, including vesicular transport, forming the mitotic spindle and in cytokinesis. Several drugs including vincristine and colcemid are similar to nocodazole in that they interfere with microtubule polymerization.
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nocodazole
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