| Weight | 295.426 g/mol |
|---|---|
| Formula | C20H25NO |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 7 |
Normethadone (467-85-6)
nor-methadone · 6-dimethylamino-4,4-diphenylhexan-3-one · normethadone hydrochloride
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- Identification and quantitative determination of some metabolites of methadone, isomethadone and normethadone. (Journal of Pharmacy and Pharmacology, 1971)
- The role of naloxone infusions in the treatment of overdoses of long half-life narcotic agonists: application to nor-methadone. (British Journal of Clinical Pharmacology, 1983)
- The influence of methyl substitution on the N-demethylation and N-oxidation of normethadone in animal species. (Journal of Pharmacy and Pharmacology, 1971)
- Crystal Structures of Synthetic Analgesics. VI. Normethadone Hydrochloride. (Acta Chemica Scandinavica, 1976)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - nor-methadone
- 6-dimethylamino-4,4-diphenylhexan-3-one
- normethadone hydrochloride
-
SMILESCCC(=O)C(CCN(C)C)(C1=CC=CC=C1)C2=CC=CC=C2
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InChIKeyWCJFBSYALHQBSK-UHFFFAOYSA-N
- Pubchem - Normethadone
- Wikipedia - normethadone
Normethadone (INN, BAN; brand names Cophylac, Dacartil, Eucopon, Mepidon, Noramidone, Normedon, and others), also known as desmethylmethadone or phenyldimazone, is a synthetic opioid analgesic and antitussive agent. Normethadone is listed under the Single Convention on Narcotic Drugs 1961 and is a Schedule I Narcotic controlled substance in the United States, with a DEA ACSCN of 9635 and an annual manufacturing quota of 2 grams. The salts in use are the hydrobromide (free base conversion ratio 0.785), hydrochloride (0.890), methyliodide (0.675), oxalate (0.766), picrate (0.563), and the 2,6-ditertbutylnapthalindisulphonate (0.480)
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Synthesis
benzene
+
Reactant
(Friedel-Crafts alkylation)
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