| Weight | 440.584 g/mol |
|---|---|
| Formula | C26H36N2O4 |
| Hydrogen Acceptors | 6 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 13 |
Norverapamil (67018-85-3)
D 591 · norverapamil, (+-)-isomer · norverapamil monohydrochloride
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- Cytochrome P450 isoforms involved in metabolism of the enantiomers of verapamil and norverapamil (British Journal of Clinical Pharmacology, 2001)
- High-performance liquid chromatographic analysis of verapamil. II. Simultaneous quantitation of verapamil and its active metabolite, norverapamil. (Journal of Chromatography B: Biomedical Sciences and Applications, 1980)
- Rapid high-performance liquid chromatographic method for the measurement of verapamil and norverapamil in blood plasma or serum. (Journal of Chromatography A, 1981)
- Pharmacokinetics of verapamil and norverapamil from controlled release floating pellets in humans. (European Journal of Pharmaceutics and Biopharmaceutics, 2002)
- Verapamil and norverapamil plasma concentrations during long-term therapy in patients with hypertrophic obstructive cardiomyopathy. (Journal of Cardiovascular Pharmacology, 1980)
- Verapamil, and its metabolite norverapamil, inhibit macrophage-induced, bacterial efflux pump-mediated tolerance to multiple anti-tubercular drugs (The Journal of Infectious Diseases, 2014)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - D 591
- norverapamil, (+-)-isomer
- norverapamil monohydrochloride
- N-demethylverapamil
-
SMILESCC(C)C(CCCNCCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC
-
InChIKeyUPKQNCPKPOLASS-UHFFFAOYSA-N
- Pubchem - Norverapamil
- Wikipedia - norverapamil
Norverapamil is a calcium channel blocker. It is the main active metabolite of verapamil.
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