Ornidazole (16773-42-5)

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Suppliers

• Sigma-Aldrich - Ornidazole
  55.20 USD
• Fisher Scientific - Search for Ornidazole
• TCI - Ornidazole
  45.00 - 154.00 USD

Most-cited Publications

• Ornidazole for Prophylaxis of Postoperative Crohn's Disease Recurrence: A Randomized, Double-Blind, Placebo-Controlled Trial (Gastroenterology, 2005)
• Comparative Pharmacokinetic Studies of Ornidazole and Metronidazole in Man (Chemotherapy, 1976)
• The ICH guidance in practice: stress degradation studies on ornidazole and development of a validated stability-indicating assay (Journal of Pharmaceutical and Biomedical Analysis, 2001)
• Synthesis and characterization of pH-sensitive hydrogel composed of carboxymethyl chitosan for colon targeted delivery of ornidazole. (Carbohydrate Research, 2012)
• Susceptibility of Anaerobic Bacteria to Metronidazole, Ornidazole, and Tinidazole and Routine Susceptibility Testing by Standardized Methods (Antimicrobial Agents and Chemotherapy, 1977)
• Induction of reversible infertility in male rats by oral ornidazole and its effects on sperm motility and epididymal secretions (Reproduction, 1994)

Areas of Application

Safety

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Trends

Alternate Names

• Tiberal
• Ro 7-0207
• Ro-70207
• Ro7 0207
• Ro 70207
• Ro70207
• Ro7-0207
• Ro 7 0207
• SMILES
  CC1=NC=C(N1CC(CCl)O)[N+](=O)[O-]
• InChIKey
  IPWKIXLWTCNBKN-UHFFFAOYSA-N

External Links

• Pubchem - Ornidazole
• Wikipedia - ornidazole
  Ornidazole is a antibiotic used to treat some protozoan infections. It has also been investigated for use in Crohn's disease after bowel resection. Synthesis is a straightforward reaction between 2-methyl-nitroimidazole and epichlorohydrin under acid catalyst conditions.

Synthesis

Reactant  +  Dichloromethane (Grignard alcohol)

Synthesis of Ornidazole ›

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dimetridazole (551-92-8)

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89128-08-5 (89128-08-5)

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13230-22-3 (13230-22-3)

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5,6,7,8-Tetrahydroimidazo[1,2-a]pyridin-3-amine dihydrochloride (1338709-39-9)

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5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-amine (1177321-97-9)

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1,2-Dimethyl-4-nitro-1H-imidazole (13230-04-1)

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1,4-dimethyl-5-nitroimidazole (57658-79-4)

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1-METHYL-5-NITROIMIDAZOLE (3034-42-2)

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22813-31-6 (22813-31-6)

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UNII-ZEC0WCC7UA (71002-10-3)

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Ornidazole

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