Weight | 563.577 g/mol |
---|---|
Formula | C29H43BrN2O4 |
Hydrogen Acceptors | 4 |
Hydrogen Donors | 1 |
Aromatic Rings | 2 |
Rotatable Bonds | 16 |
Otilonium Bromide (26095-59-0)
Spasmomen · N-diethylmethylammoniummethyl-p-(2-(N-octyloxy)benzoyl)aminobenzoate bromide · octylonium
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- Otilonium bromide in irritable bowel syndrome: a doubleblind, placebocontrolled, 15week study (Alimentary Pharmacology & Therapeutics, 1998)
- Randomised clinical trial: otilonium bromide improves frequency of abdominal pain, severity of distention and time to relapse in patients with irritable bowel syndrome (Alimentary Pharmacology & Therapeutics, 2011)
- Extended analysis of a double-blind, placebo-controlled, 15-week study with otilonium bromide in irritable bowel syndrome. (European Journal of Gastroenterology & Hepatology, 2002)
- Antimuscarinic, calcium channel blocker and tachykinin NK2 receptor antagonist actions of otilonium bromide in the circular muscle of guinea-pig colon. (Naunyn-schmiedebergs Archives of Pharmacology, 1999)
- Clinical and functional evaluation of the efficacy of otilonium bromide: a multicenter study in Italy. (The Italian journal of gastroenterology, 1991)
- A DISTRIBUTION STUDY WITH 14 C-OTILONIUM BROMIDE IN THE RAT: EVIDENCE FOR SELECTIVE TROPISM FOR LARGE INTESTINE AFTER ORAL ADMINISTRATION (Drug Metabolism and Disposition, 2000)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Spasmomen
- N-diethylmethylammoniummethyl-p-(2-(N-octyloxy)benzoyl)aminobenzoate bromide
- octylonium
- octylonium bromide
- octylonium iodide
-
SMILESCCCCCCCCOC1=CC=CC=C1C(=O)NC2=CC=C(C=C2)C(=O)OCC[N+](C)(CC)CC.[Br-]
-
InChIKeyVWZPIJGXYWHBOW-UHFFFAOYSA-N
- Pubchem - Otilonium Bromide
- Wikipedia - otilonium bromide
Otilonium bromide is an antimuscarinic and calcium channel blocker used to relieve spasmodic pain of the gut, especially in irritable bowel syndrome. It is sold under the trade name Spasmoctyl 40, and as Doralin in Greece.
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