Weight | 142.114 g/mol |
---|---|
Formula | C5H6N2O3 |
Hydrogen Acceptors | 5 |
Hydrogen Donors | 1 |
Aromatic Rings | 0 |
Rotatable Bonds | 2 |
Oxyma (3849-21-6, 56503-39-0)
ethyl 2-cyano-2-(hydroxyimino)acetate
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - ethyl 2-cyano-2-(hydroxyimino)acetate
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SMILESCCOC(=O)C(=NO)C#N
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InChIKeyLCFXLZAXGXOXAP-UHFFFAOYSA-N
- Pubchem - Oxyma
- Wikipedia - ethyl cyanohydroxyiminoacetate
Ethyl cyanohydroxyiminoacetate (oxyma) is the oxime of ethyl cyanoacetate and finds use as an additive for carbodiimides, such as dicyclohexylcarbodiimide (DCC) in peptide synthesis. It acts as a neutralizing reagent for the basicity or nucleophilicity of the DCC due to its pronounced acidity (pKa 4.60) and suppresses base-induced side reactions, in particular racemization.
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