Weight | 152.113 g/mol |
---|---|
Formula | C5H4N4O2 |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 3 |
Aromatic Rings | 0 |
Rotatable Bonds | 0 |
Oxypurinol (2465-59-0)
Oxipurinol · Alloxanthine
Score:
#1352 in Biochemistry
,
#3281 in Biology
,
#4097 in Chemistry
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- Sigma-Aldrich - Oxypurinol75.00 - 540.00 USD
- Fisher Scientific - Search for Oxypurinol
- TCI - Search for Oxypurinol
- Allopurinol and oxypurinol are hydroxyl radical scavengers (FEBS Letters, 1987)
- Impact of oxypurinol in patients with symptomatic heart failure. Results of the OPT-CHF study. (Journal of the American College of Cardiology, 2008)
- Xanthine Oxidase Inhibition With Oxypurinol Improves Endothelial Vasodilator Function in Hypercholesterolemic but Not in Hypertensive Patients (Hypertension, 1997)
- Role of xanthine oxidase inhibitor as free radical scavenger: A novel mechanism of action of allopurinol and oxypurinol in myocardial salvage (Biochemical and Biophysical Research Communications, 1987)
- Renal clearance of oxipurinol, the chief metabolite of allopurinol (The American Journal of Medicine, 1968)
- Tight-binding inhibitorsII: Non-steady state nature of inhibition of milk xanthine oxidase by allopurinol and alloxanthine and of human erythrocytic adenosine deaminase by coformycin (Biochemical Pharmacology, 1975)
-
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Oxipurinol
- Alloxanthine
-
SMILESC1=C2C(=NC(=O)NC2=O)NN1
-
InChIKeyHXNFUBHNUDHIGC-UHFFFAOYSA-N
- Pubchem - Oxypurinol
- Wikipedia - oxypurinol
Oxipurinol (INN, or oxypurinol USAN) is an inhibitor of xanthine oxidase. It is an active metabolite of allopurinol and it is cleared renally. In cases of renal disease, this metabolite will accumulate to toxic levels.
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