Weight | 354.469 g/mol |
---|---|
Formula | C22H27FN2O |
Hydrogen Acceptors | 2 |
Hydrogen Donors | 0 |
Aromatic Rings | 2 |
Rotatable Bonds | 6 |
p-Fluorofentanyl (90736-23-5)
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- Interaction of p-fluorofentanyl on cloned human opioid receptors and exploration of the role of Trp-318 and His-319 in mu-opioid receptor selectivity. (Journal of Pharmacology and Experimental Therapeutics, 2000)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCCC(=O)N(C1CCN(CC1)CCC2=CC=CC=C2)C3=CC=C(C=C3)F
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InChIKeyKXUBAVLIJFTASZ-UHFFFAOYSA-N
- Pubchem - p-Fluorofentanyl
- Wikipedia - p-fluorofentanyl
Parafluorofentanyl (4-Fluorofentanyl) is an opioid analgesic being an analogue of fentanyl developed by Janssen Pharmaceutica in the 1960s. 4-Fluorofentanyl was sold briefly on the US black market in the early 1980s, before the introduction of the Federal Analog Act which for the first time attempted to control entire families of drugs based on their structural similarity rather than scheduling each drug individually as they appeared. 4-Fluorofentanyl is made with the same synthetic route as fentanyl, but by substituting para-fluoroaniline for aniline in the synthesis.
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Synthesis
4-Fluorophenylboronic acid
+
Reactant
(Chan-Lam coupling reaction)
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