| Weight | 337.423 g/mol |
|---|---|
| Formula | C20H23N3O2 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 2 |
Phenserine (101246-66-6, 159652-53-6)
Score:
#189 in Neurology
,
#848 in Neuroscience
,
#3728 in Biology
,
#4692 in Chemistry
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- Phenserine regulates translation of -amyloid precursor protein mRNA by a putative interleukin-1 responsive element, a target for drug development (Proceedings of the National Academy of Sciences of the United States of America, 2001)
- Synthesis of novel phenserine-based-selective inhibitors of butyrylcholinesterase for Alzheimer's disease. (Journal of Medicinal Chemistry, 1999)
- Phenserine and ring C hetero-analogues: drug candidates for the treatment of Alzheimer's disease. (Medicinal Research Reviews, 1995)
- Asymmetric Synthesis of Pyrrolidinoindolines. Application for the Practical Total Synthesis of ()-Phenserine (Journal of the American Chemical Society, 2004)
- Effect of phenserine treatment on brain functional activity and amyloid in Alzheimer's disease (Annals of Neurology, 2008)
- The Experimental Alzheimer's Disease Drug Posiphen [(+)-Phenserine] Lowers Amyloid- Peptide Levels in Cell Culture and Mice (Journal of Pharmacology and Experimental Therapeutics, 2006)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC12CCN(C1N(C3=C2C=C(C=C3)OC(=O)NC4=CC=CC=C4)C)C
-
InChIKeyPBHFNBQPZCRWQP-UHFFFAOYSA-N
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