| Weight | 251.713 g/mol |
|---|---|
| Formula | C13H14ClNO2 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 3 |
Pirprofen (31793-07-4)
2-(3-chloro-4-(3-pyrroli-1-yl)phenyl)propionic acid · Rengasil · SU-21524
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- Inhibition of mitochondrial beta-oxidation of fatty acids by pirprofen. Role in microvesicular steatosis due to this nonsteroidal anti-inflammatory drug. (Journal of Pharmacology and Experimental Therapeutics, 1987)
- Diclofenac and pirprofen modify pituitary and hypothalamic beta-endorphin concentrations (Pharmacological Research Communications, 1985)
- Pirprofen-induced fulminant hepatitis (Gastroenterology, 1985)
- Binding of pirprofen to human serum albumin studied by dialysis and spectroscopy techniques (Biochemical Pharmacology, 1989)
- Glucuronidation of 2-arylpropionic acids pirprofen, flurbiprofen, and ibuprofen by liver microsomes. (Drug Metabolism and Disposition, 1990)
- Inhibition of prostaglandin synthase by pirprofen. Studies with sheep seminal vesicle enzyme. (Biochimica et Biophysica Acta, 1975)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - 2-(3-chloro-4-(3-pyrroli-1-yl)phenyl)propionic acid
- Rengasil
- SU-21524
-
SMILESCC(C1=CC(=C(C=C1)N2CC=CC2)Cl)C(=O)O
-
InChIKeyPIDSZXPFGCURGN-UHFFFAOYSA-N
- Pubchem - Pirprofen
- Wikipedia - pirprofen
Pirprofen was a nonsteroidal anti-inflammatory drug (NSAID) that was brought to market by Ciba-Geigy in 1982 as a treatment for arthritis and pain. Its label was restricted after adverse events arose, including some cases of fatal liver toxicity. Ciba-Geigy voluntarily withdrew the drug from the market worldwide in 1990.
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