| Weight | 381.354 g/mol |
|---|---|
| Formula | C18H18F3N3O3 |
| Hydrogen Acceptors | 6 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 6 |
Pleconaril (153168-05-9)
Picovir · 3-(3,5-dimethyl-4((3-(3-methyl-5-isoxazolyl)propyl)phenyl)-5-trifluoromethyl)-1,2,4-oxadiazole
Score:
#469 in Microbiology
,
#3717 in Biology
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- Treatment of Potentially Life-Threatening Enterovirus Infections with Pleconaril (Clinical Infectious Diseases, 2001)
- Activity of pleconaril against enteroviruses. (Antimicrobial Agents and Chemotherapy, 1999)
- Efficacy and Safety of Oral Pleconaril for Treatment of Colds Due to Picornaviruses in Adults: Results of 2 Double-Blind, Randomized, Placebo-Controlled Trials (Clinical Infectious Diseases, 2003)
- In vitro activity of pleconaril and AG7088 against selected serotypes and clinical isolates of human rhinoviruses. (Antiviral Research, 2000)
- Double blind placebo-controlled trial of pleconaril in infants with enterovirus meningitis (Pediatric Infectious Disease Journal, 2003)
- Enteroviral Meningitis: Natural History and Outcome of Pleconaril Therapy (Antimicrobial Agents and Chemotherapy, 2006)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Picovir
- 3-(3,5-dimethyl-4((3-(3-methyl-5-isoxazolyl)propyl)phenyl)-5-trifluoromethyl)-1,2,4-oxadiazole
-
SMILESCC1=CC(=CC(=C1OCCCC2=CC(=NO2)C)C)C3=NOC(=N3)C(F)(F)F
-
InChIKeyKQOXLKOJHVFTRN-UHFFFAOYSA-N
- Pubchem - Pleconaril
- Wikipedia - pleconaril
Pleconaril (Picovir) is an antiviral drug that was being developed by Schering-Plough for prevention of asthma exacerbations and common cold symptoms in patients exposed to picornavirus respiratory infections. Pleconaril, administered either orally or intranasally, is active against viruses in the Picornaviridae family, including Enterovirus and Rhinovirus. It has shown useful activity against the dangerous strain enterovirus D68.
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Pleconaril
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