| Weight | 502.796 g/mol |
|---|---|
| Formula | C28H54N8 |
| Hydrogen Acceptors | 8 |
| Hydrogen Donors | 6 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 4 |
Plerixafor (155148-31-5, 110078-46-1)
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- Plerixafor and G-CSF versus placebo and G-CSF to mobilize hematopoietic stem cells for autologous stem cell transplantation in patients with multiple myeloma. (Blood, 2009)
- Phase III Prospective Randomized Double-Blind Placebo-Controlled Trial of Plerixafor Plus Granulocyte Colony-Stimulating Factor Compared With Placebo Plus Granulocyte Colony-Stimulating Factor for Autologous Stem-Cell Mobilization and Transplantation for Patients With Non-Hodgkin's Lymphoma (Journal of Clinical Oncology, 2009)
- A phase 1/2 study of chemosensitization with the CXCR4 antagonist plerixafor in relapsed or refractory acute myeloid leukemia (Blood, 2012)
- International myeloma working group (IMWG) consensus statement and guidelines regarding the current status of stem cell collection and high-dose therapy for multiple myeloma and the role of plerixafor (AMD 3100). (Leukemia, 2009)
- Safety and preliminary efficacy of plerixafor (mozobil) in combination with chemotherapy and G-CSF: An open-label, multicenter, exploratory trial in patients with multiple myeloma and non-Hodgkin's lymphoma undergoing stem cell mobilization (Bone Marrow Transplantation, 2010)
- Plerixafor (AMD3100) and granulocyte colony-stimulating factor (G-CSF) mobilize different CD34+ cell populations based on global gene and microRNA expression signatures (Blood, 2009)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
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- Pubchem - Plerixafor
- Wikipedia - plerixafor
Plerixafor (INN and USAN, trade name Mozobil) is an immunostimulant used to mobilize hematopoietic stem cells in cancer patients into the bloodstream. The stem cells are then extracted from the blood and transplanted back to the patient. The drug was developed by AnorMED, which was subsequently bought by Genzyme.
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(775561-26-7)
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(R)-1-(1-benzylpyrrolidin-3-yl)piperazine
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611225-86-6
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1-[4-(trifluoromethyl)benzyl]piperazine
(107890-32-4)
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1-benzylpiperidin-3-amine
(60407-35-4)
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1-benzylpiperidin-3-amine
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1-(4-Fluorobenzyl)piperazine
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1-(4-Chlorobenzyl)piperazine
(23145-88-2)
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1-benzyl-4-hydrazinylpiperidine dihydrochloride
(83949-42-2)
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1-Benzyl-4-hydrazinopiperidine tri hydrochloride
(83949-42-2)
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1-(2-Methylbenzyl)piperazine
(5321-47-1)
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1-(2-methylbenzyl)piperazine dihydrochloride
(5321-51-7)
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AC1LU345
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n-benzyl-n-ethylpiperidin-4-amine
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(229323-04-0)
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(871112-85-5)
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(124257-62-1)
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(119929-87-2)
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Ambcb4004078
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(189333-49-1)
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139-08-2
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N,N-dimethyl-4-(piperazin-1-ylmethyl)aniline
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2-(1-benzylpiperidin-2-yl)ethanamine
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[3-(1,3-dihydro-2H-isoindol-2-yl)propyl]amine dihydrochloride
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N-(4-METHYLBENZYL)-1-BUTANAMINE HYDROCHLORIDE
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101-32-6
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N-benzyl-2-chloro-N-(2-chloroethyl)ethanamine
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1-(4-FLUOROBENZYL)PIPERIDIN-3-AMINE DIHYDROCHLORIDE
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2032-33-9
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N-(4-METHYLBENZYL)-2-BUTANAMINE HYDROCHLORIDE
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1-(2-bromobenzyl)piperazine
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91560-85-9
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[2-(1-benzyl-3-pyrrolidinyl)ethyl]amine dihydrochloride
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3-[(4-methylbenzyl)amino]-1-propanol hydrochloride
(1269054-83-2)
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Plerixafor
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