| Weight | 273.248 g/mol |
|---|---|
| Formula | C13H11N3O4 |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 1 |
Pomalidomide (19171-19-8)
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- Sigma-Aldrich - Pomalidomide105.50 - 426.50 USD
- Fisher Scientific - Search for Pomalidomide
- TCI - Pomalidomide198.00 - 594.00 USD
- Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide (Blood, 2011)
- Pomalidomide plus low-dose dexamethasone versus high-dose dexamethasone alone for patients with relapsed and refractory multiple myeloma (MM-003): a randomised, open-label, phase 3 trial (Lancet Oncology, 2013)
- Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide (Leukemia, 2012)
- Pomalidomide (CC4047) Plus Low-Dose Dexamethasone As Therapy for Relapsed Multiple Myeloma (Journal of Clinical Oncology, 2009)
- The anti-cancer agents lenalidomide and pomalidomide inhibit the proliferation and function of T regulatory cells (Cancer Immunology, Immunotherapy, 2009)
- Pomalidomide and dexamethasone in the treatment of AL amyloidosis: results of a phase 1 and 2 trial (Blood, 2007)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)N
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InChIKeyUVSMNLNDYGZFPF-UHFFFAOYSA-N
- Pubchem - Pomalidomide
- Wikipedia - pomalidomide
Pomalidomide (INN; marketed as Pomalyst in the U.S. and Imnovid in the EU and Russia) is a derivative of thalidomide marketed by Celgene. It is anti-angiogenic and also acts as an immunomodulator.
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Pomalidomide
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