Weight | 266.341 g/mol |
---|---|
Formula | C14H22N2O3 |
Hydrogen Acceptors | 4 |
Hydrogen Donors | 3 |
Aromatic Rings | 1 |
Rotatable Bonds | 7 |
practolol (6673-35-4)
ICI-50172 · Dalzic · Eralzdin Practolol
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- Sigma-Aldrich - practolol40.20 - 164.00 USD
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- Letter: Sclerosing peritonitis and practolol. (The Lancet, 1975)
- SCLEROSING PERITONITIS, AN UNUSUAL REACTION TO A -ADRENERGIC-BLOCKING DRUG (PRACTOLOL) (The Lancet, 1974)
- Untoward effects associated with practolol administration: oculomucocutaneous syndrome. (BMJ, 1975)
- Cutaneous and Ocular Reactions to Practolol (BMJ, 1974)
- Letter: Practolol in the control of intraocular tension. (The Lancet, 1974)
- Immediate haemodynamic effects of propranolol, practolol, pindolol, atenolol and ICI 89,406 in healthy volunteers (European Journal of Clinical Pharmacology, 1979)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - ICI-50172
- Dalzic
- Eralzdin Practolol
- ICI 50172
- ICI50172
-
SMILESCC(C)NCC(COC1=CC=C(C=C1)NC(=O)C)O
-
InChIKeyDURULFYMVIFBIR-UHFFFAOYSA-N
- Pubchem - practolol
- Wikipedia - practolol
Practolol (Eraldin, Dalzic, Praktol, Cardiol, Pralon, Cordialina, Eraldina, Teranol) is a selective beta blocker (beta-1 blocker) that has been used in the emergency treatment of cardiac arrhythmias. Practolol is no longer used as it is highly toxic despite the similarity of its chemical formula to propranolol. After its introduction, keratoconjunctivitis sicca, conjunctival scarring, fibrosis, metaplasia, and shrinkage developed in 27 patients as an adverse reaction to practolol.
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Synthesis
ISOPROPYLAMINE
+
Reactant
(Alkylation of primary amines)
Acetaminophen
+
Reactant
(Williamson ether)
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