Weight | 481.512 g/mol |
---|---|
Formula | C27H23N5O4 |
Hydrogen Acceptors | 7 |
Hydrogen Donors | 2 |
Aromatic Rings | 5 |
Rotatable Bonds | 9 |
Pranlukast (150821-03-7, 103177-37-3)
ONO-RS 411 · SB 205312 · 8-(4 (4-phenylbutoxy)benzoyl)amino-2-(tetrazol-5'-yl)-4-oxo-4H-1-benzopyran
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- Effect of surface morphology of carrier lactose on dry powder inhalation property of pranlukast hydrate (International Journal of Pharmaceutics, 1998)
- Persistent airway eosinophilia after leukotriene (LT) D4 administration in the guinea pig: modulation by the LTD4 receptor antagonist, pranlukast, or an interleukin-5 monoclonal antibody. (American Journal of Respiratory and Critical Care Medicine, 1996)
- Effect of the leukotriene receptor antagonist pranlukast on cellular infiltration in the bronchial mucosa of patients with asthma. (Thorax, 1998)
- Leukotriene C4 synthase gene A(-444)C polymorphism and clinical response to a CYS-LT1 antagonist, pranlukast, in Japanese patients with moderate asthma (Pharmacogenetics, 2002)
- Pranlukast, a cysteinyl leukotriene receptor antagonist, attenuates allergen-induced early- and late-phase bronchoconstriction and airway hyperresponsiveness in asthmatic subjects (The Journal of Allergy and Clinical Immunology, 1998)
- Pranlukast, a novel leukotriene receptor antagonist: results of the first European, placebo controlled, multicentre clinical study in asthma. (Thorax, 1997)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - ONO-RS 411
- SB 205312
- 8-(4 (4-phenylbutoxy)benzoyl)amino-2-(tetrazol-5'-yl)-4-oxo-4H-1-benzopyran
- ONO-RS-411
- ONO-1078
- ONO 1078
-
SMILESC1=CC=C(C=C1)CCCCOC2=CC=C(C=C2)C(=O)NC3=CC=CC4=C3OC(=CC4=O)C5=NNN=N5
-
InChIKeyNBQKINXMPLXUET-UHFFFAOYSA-N
- Pubchem - Pranlukast
- Wikipedia - pranlukast
Pranlukast (brand name Onon, ) is a cysteinyl leukotriene receptor-1 antagonist. This drug works similarly to Merck & Co.'s montelukast (Singulair). It is widely used in Japan.
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