| Weight | 516.857 g/mol |
|---|---|
| Formula | C31H48O2S2 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 4 |
probucol (23288-49-5)
Lorelco · Superlipid · Biphenabid
Score:
#644 in Neuroscience
,
#1130 in Biochemistry
,
#2880 in Biology
,
#3604 in Chemistry
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- Antiatherogenic effect of probucol unrelated to its hypocholesterolemic effect: evidence that antioxidants in vivo can selectively inhibit low density lipoprotein degradation in macrophage-rich fatty streaks and slow the progression of atherosclerosis in the Watanabe heritable hyperlipidemic rabbit. (Proceedings of the National Academy of Sciences of the United States of America, 1987)
- Probucol prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbit, an animal model for familial hypercholesterolemia. (Proceedings of the National Academy of Sciences of the United States of America, 1987)
- Probucol and Multivitamins in the Prevention of Restenosis after Coronary Angioplasty (The New England Journal of Medicine, 1997)
- Probucol inhibits oxidative modification of low density lipoprotein. (Journal of Clinical Investigation, 1986)
- Probucol Protects Against Adriamycin Cardiomyopathy Without Interfering With Its Antitumor Effect (Circulation, 1995)
- The effect of probucol on femoral atherosclerosis: the Probucol Quantitative Regression Swedish Trial (PQRST). (American Journal of Cardiology, 1994)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Lorelco
- Superlipid
- Biphenabid
- Panavir
- DH581
- Lurselle
- DH 581
- DH-581
-
SMILESCC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)SC(C)(C)SC2=CC(=C(C(=C2)C(C)(C)C)O)C(C)(C)C
-
InChIKeyFYPMFJGVHOHGLL-UHFFFAOYSA-N
- Pubchem - probucol
- Wikipedia - probucol
Probucol is an anti-hyperlipidemic drug initially developed in the treatment of coronary artery disease. However, clinical trials were stopped after it was found that it may lower HDL in patients with a previous history of heart disease. Probucol was initially developed in the 1970s by a chemical company to maximize airplane tire longevity.
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probucol
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