Weight | 844.45 g/mol |
---|---|
Formula | C46H58ClN5O8 |
Hydrogen Acceptors | 11 |
Hydrogen Donors | 1 |
Aromatic Rings | 4 |
Rotatable Bonds | 21 |
PROGLUMETACIN (57132-53-3)
protacine · Protaxil · 3'-(4-(2-(1-p-chlorobenzoyl-5-methoxy-2-methylindol-3-ylacetoxy)ethyl)piperazin-1-yl)propyl-4-benzamido-N,N-dipropylglutaramate (+-) dimaleate
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- Double-blind clinical evaluation of a new anti-inflammatory drug, protacine, versus indomethacin (Current Medical Research and Opinion, 1979)
- Double-blind clinical trial of protacine versus oxyphenbutazone in rheumatic disorders. (1980)
- A 3-month, double-blind study of proglumetacin and naproxen in the treatment of rheumatoid arthritis (Current Medical Research and Opinion, 1982)
- Pharmacological study of a new non-steroidal anti-inflammatory drug: protacine (CR 604). (Drug Research, 1979)
- Preliminary double-blind evaluation of a new, non-steroidal anti-inflammatory drug: protacine. (1980)
- Studies on the safety of a new non-steroidal anti-inflammatory drug: protacine (CR 604). (Drug Research, 1979)
-
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - protacine
- Protaxil
- 3'-(4-(2-(1-p-chlorobenzoyl-5-methoxy-2-methylindol-3-ylacetoxy)ethyl)piperazin-1-yl)propyl-4-benzamido-N,N-dipropylglutaramate (+-) dimaleate
- Protaxon
- proglumetacin maleate
- Prodamox
- proglumetacin dimaleate
-
SMILESCCCN(CCC)C(=O)C(CCC(=O)OCCCN1CCN(CC1)CCOC(=O)CC2=C(N(C3=C2C=C(C=C3)OC)C(=O)C4=CC=C(C=C4)Cl)C)NC(=O)C5=CC=CC=C5
-
InChIKeyPTXGHCGBYMQQIG-UHFFFAOYSA-N
- Pubchem - PROGLUMETACIN
- Wikipedia - proglumetacin
Proglumetacin (usually as the maleate salt, trade names Afloxan, Protaxon and Proxil) is a nonsteroidal anti-inflammatory drug (NSAID). It is metabolized in the body to indometacin and proglumide, a drug with antisecretory effects that helps prevent injury to the stomach lining.
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