Weight | 306.366 g/mol |
---|---|
Formula | C15H22N4O3 |
Hydrogen Acceptors | 7 |
Hydrogen Donors | 0 |
Aromatic Rings | 2 |
Rotatable Bonds | 7 |
propentofylline (55242-55-2)
HWA 285 · 1-(5'-oxohexyl)-3-methyl-7-propylxanthine · HWA-285
Score:
#994 in Neuroscience
,
#4351 in Biology
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- Propentofylline, a Glial Modulating Agent, Exhibits Antiallodynic Properties in a Rat Model of Neuropathic Pain (Journal of Pharmacology and Experimental Therapeutics, 2001)
- Attenuation of morphine tolerance, withdrawal-induced hyperalgesia, and associated spinal inflammatory immune responses by propentofylline in rats. (Neuropsychopharmacology, 2004)
- Ischemia-Induced Neuronal Cell Death, Calcium Accumulation, and Glial Response in the Hippocampus of the Mongolian Gerbil and Protection by Propentofylline (HWA 285) (Journal of Cerebral Blood Flow and Metabolism, 1987)
- Anti-hyperalgesic and morphine-sparing actions of propentofylline following peripheral nerve injury in rats: mechanistic implications of spinal glia and proinflammatory cytokines. (Pain, 2003)
- Protective effect of adenosine and a novel xanthine derivative propentofylline on the cell damage after bilateral carotid occlusion in the gerbil hippocampus (Brain Research, 1990)
- Effect of propentofylline (HWA 285) on extracellular purines and excitatory amino acids in CA1 of rat hippocampus during transient ischaemia (British Journal of Pharmacology, 1990)
-
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - HWA 285
- 1-(5'-oxohexyl)-3-methyl-7-propylxanthine
- HWA-285
-
SMILESCCCN1C=NC2=C1C(=O)N(C(=O)N2C)CCCCC(=O)C
-
InChIKeyRBQOQRRFDPXAGN-UHFFFAOYSA-N
- Pubchem - propentofylline
- Wikipedia - propentofylline
Propentofylline (HWA 285) is a xanthine derivative with purported neuroprotective effects.
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