| Weight | 390.067 g/mol |
|---|---|
| Formula | C5H13O14P3 |
| Hydrogen Acceptors | 9 |
| Hydrogen Donors | 7 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 7 |
PRPP
Phosphoribosyl Pyrophosphate
7540-64-9, 97-55-2, 13270-65-0
Score:
#1205 in Biochemistry
,
#3029 in Biology
,
#3785 in Chemistry
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- The regulation of activity of phosphoribosyl-pyrophosphate amidotransferase by purine ribonacleotides: a potential feedback control of purine biosyntoesis. (Journal of Biological Chemistry, 1959)
- Regulation of the synthesis of 5-phosphoribosyl-I-pyrophosphate in intact red blood cells and in cell-free preparations. (Biochimica et Biophysica Acta, 1969)
- SYNTHESIS OF 5-PHOSPHORIBOSYL 1-PYROPHOSPHATE FROM GLUCOSE IN EHRLICH ASCITES TUMOR CELLS IN VITRO. (Journal of Biological Chemistry, 1965)
- Purification and properties of 5-phosphoribosyl pyrophosphate amidotransferase from adenocarcinoma 755 cells. (Biochemistry, 1969)
- Mutations in PRPS1, Which Encodes the Phosphoribosyl Pyrophosphate Synthetase Enzyme Critical for Nucleotide Biosynthesis, Cause Hereditary Peripheral Neuropathy with Hearing Loss and Optic Neuropathy (CMTX5) (American Journal of Human Genetics, 2007)
- Involvement of Atp, 5-Phosphoribosyl-Pyrophosphate and L-Azaserine in the Enzymatic Formation of Glycinamide Ribotide Intermediates in Inosinic Acid Biosynthesis (Journal of the American Chemical Society, 1955)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Phosphoribosyl Pyrophosphate
-
SMILESC(C1C(C(C(O1)OP(=O)(O)OP(=O)(O)O)O)O)OP(=O)(O)O
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InChIKeyPQGCEDQWHSBAJP-UHFFFAOYSA-N
- Pubchem - PRPP
- Wikipedia - Alpha-Phosphoribosylpyrophosphoric Acid
Phosphoribosyl pyrophosphate (PRPP) is a pentosephosphate. It is formed from ribose 5-phosphate by the enzyme ribose-phosphate diphosphokinase. It plays a role in transferring phospho-ribose groups in several reactions: In de novo generation of purines, the enzyme amidophosphoribosyltransferase acts upon PRPP to create phosphoribosylamine.
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