| Weight | 123.115 g/mol |
|---|---|
| Formula | C5H5N3O |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 1 |
Pyrazinamide (98-96-4)
Tisamid
Score:
#92 in Microbiology
,
#1085 in Biology
,
#1220 in Chemistry
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- Mutations in pncA, a gene encoding pyrazinamidase/nicotinamidase, cause resistance to the antituberculous drug pyrazinamide in tubercle bacillus. (Nature Medicine, 1996)
- The curious characteristics of pyrazinamide: a review. (International Journal of Tuberculosis and Lung Disease, 2003)
- Pyrazinamide Inhibits Trans-Translation in Mycobacterium tuberculosis (Science, 2011)
- Mode of action of pyrazinamide: disruption of Mycobacterium tuberculosis membrane transport and energetics by pyrazinoic acid (Journal of Antimicrobial Chemotherapy, 2003)
- 14-day bactericidal activity of PA-824, bedaquiline, pyrazinamide, and moxifloxacin combinations: a randomised trial (The Lancet, 2012)
- Rifampin and Pyrazinamide vs Isoniazid for Prevention of Tuberculosis in HIV-Infected Persons: An International Randomized Trial (JAMA, 2000)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Tisamid
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SMILESC1=CN=C(C=N1)C(=O)N
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InChIKeyIPEHBUMCGVEMRF-UHFFFAOYSA-N
- Pubchem - Pyrazinamide
- Wikipedia - pyrazinamide
Pyrazinamide is a medication used to treat tuberculosis. For active tuberculosis it is often used together with rifampin, isoniazid, and either streptomycin or ethambutol. It is not generally recommended for the treatment of latent tuberculosis.
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1 safety hazard
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3 suppliers
1H-imidazole-4,5-dicarbohydrazide
(5423-20-1)
2 alternate names
3 suppliers
1-(Pyrazin-2-yl)propan-1-one
(51369-99-4)
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(5372-23-6)
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3 suppliers
2-chloro-6-(1-pyrrolidinylcarbonyl)pyrazine
(959241-31-7)
2 alternate names
3 suppliers
2-chloro-6-[(4-methyl-1-piperazinyl)carbonyl]pyrazine
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2 alternate names
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2-chloro-6-(1-piperidinylcarbonyl)pyrazine
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(1452-77-3)
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6-Methylpyrazine-2-carboxylic acid
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3 suppliers
2-METHYLPYRAZINE
(109-08-0)
2 alternate names
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4-[(6-chloro-2-pyrazinyl)carbonyl]morpholine
(24079-32-1)
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3 suppliers
2-ACETYL-3-METHYLPYRAZINE
(23787-80-6)
2 alternate names
3 suppliers
2,5-DIMETHYLPYRAZINE
(123-32-0)
2 alternate names
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3 suppliers
1h-pyrrole-2-carbohydrazide
(50269-95-9)
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3 suppliers
1-Methyl-1H-imidazole-5-carbohydrazide
(23585-00-4)
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2,3-DIMETHYLPYRAZINE
(25704-73-8, 5910-89-4)
2 alternate names
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(1593-08-4)
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[(6-chloro-2-pyrazinyl)methyl]dimethylamine dihydrochloride
(1609400-33-0)
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2 alternate names
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2,3-Pyrazinedicarboxylic acid
(89-01-0)
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methyl pyrazine-2-carboxylate
(6164-79-0)
2 alternate names
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(34604-60-9)
2 alternate names
3 suppliers
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(108-50-9)
2 alternate names
3 suppliers
picolinohydrazide
(1452-63-7)
2 alternate names
3 suppliers
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(13051-89-3)
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methyl 5-methylpyrazine-2-carboxylate
(41110-33-2)
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(25519-55-5)
2 alternate names
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MolPort-029-998-074
2 alternate names
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(302560-90-3)
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5-CHLOROPYRAZINE-2-CARBOXYLIC ACID
(36070-80-1)
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3 suppliers
3-Aminopyrazine-2-carboxylic acid
(5424-01-1)
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Ambcb4100928
(1185033-05-9)
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imidazo[1,2-a]pyridin-2-ylmethanamine dihydrochloride
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4-Chloropyridine-2-carboxamide
(99586-65-9)
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(2016-88-8)
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(imidazo[1,2-a]pyridin-3-ylmethyl)amine hydrochloride hydrate
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(39204-47-2)
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(193534-56-4)
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2-(pyrazin-2-yl)ethanol
(6705-31-3)
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6-Chloropyrazine-2-carboxylic acid
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(62150-46-3)
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1-methylpyrrole-2-carboxamide
(64230-41-7)
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2-Propylpyrazine
(18138-03-9)
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3 suppliers
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2 alternate names
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c-(7-Methyl-imidazo[1,2-a]pyridin-2-yl)-methylamine dihydrochloride
(1284226-43-2)
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2-(chloromethyl)-5-methylpyrazine hydrochloride
(128229-06-1)
2 alternate names
3 suppliers
6-methoxypyrazine-2-carboxylic acid
(24005-61-6)
2 alternate names
3 suppliers
pyridine-2,6-dicarbohydrazide
(5112-36-7)
2 alternate names
3 suppliers
3-Methylpyrazin-2-amine
(19838-08-5)
2 alternate names
3 suppliers
2-(Pyrazin-2-yl)ethanamine
(5321-59-5)
2 alternate names
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(4177-16-6)
2 alternate names
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3-amino-5-methylpyrazine-2-carboxylic acid
(6761-50-8)
2 alternate names
3 suppliers
Quinoxaline-2-carbonyl chloride
(54745-92-5)
2 alternate names
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2-Quinoxalinecarbonyl chloride
(54745-92-5)
2 alternate names
3 suppliers
2-Mercaptomethylpyrazine
(59021-02-2)
2 alternate names
3 suppliers
2-methyl-5-pyrimidinecarbohydrazide
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2 alternate names
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4-Chloropicolinohydrazide
(73771-11-6)
2 alternate names
3 suppliers
(imidazo[1,2-a]pyridin-3-ylmethyl)methylamine dihydrochloride
(1357352-53-4)
2 alternate names
3 suppliers
Pyrazinamide
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