Weight | 189.127 g/mol |
---|---|
Formula | C5H7N3O5 |
Hydrogen Acceptors | 6 |
Hydrogen Donors | 3 |
Aromatic Rings | 1 |
Rotatable Bonds | 3 |
Quisqualate (52809-07-1)
Score:
#898 in Neuroscience
,
#3950 in Biology
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- Structure-activity relationships for amino acid transmitter candidates acting at N-methyl-D-aspartate and quisqualate receptors. (The Journal of Neuroscience, 1990)
- The ontogeny of excitatory amino acid receptors in rat forebrainI.N-methyl-d-aspartate and quisqualate receptors (Neuroscience, 1990)
- Contributions of quisqualate and NMDA receptors to the induction and expression of LTP (Science, 1988)
- Glutamate receptor channels in rat DRG neurons: Activation by kainate and quisqualate and blockade of desensitization by con A (Neuron, 1990)
- Autoradiographic characterization of N-methyl-D-aspartate-, quisqualate- and kainate-sensitive glutamate binding sites. (Journal of Pharmacology and Experimental Therapeutics, 1985)
- Allosteric potentiation of quisqualate receptors by a nootropic drug aniracetam. (The Journal of Physiology, 1990)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC(C(C(=O)O)N)N1C(=O)NC(=O)O1
-
InChIKeyASNFTDCKZKHJSW-UHFFFAOYSA-N
- Pubchem - Quisqualate
- Wikipedia - quisqualic acid
Quisqualic acid is an agonist of the AMPA, kainate, and group I metabotropic glutamate receptors. It is one of the most potent AMPA receptor agonists known. It causes excitotoxicity and is used in neuroscience to selectively destroy neurons in the brain or spinal cord.
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