| Weight | 278.352 g/mol |
|---|---|
| Formula | C15H22N2O3 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 7 |
RO 20-1724 (34185-37-0, 29925-17-5)
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- Phosphodiesterase Inhibition by Ro 20-1724 Reduces Hyper-IgE Synthesis by Atopic Dermatitis Cells In Vitro (Journal of Investigative Dermatology, 1985)
- Antipsychotic-Like Properties of Phosphodiesterase 4 Inhibitors: Evaluation of 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone (RO-20-1724) with Auditory Event-Related Potentials and Prepulse Inhibition of Startle (Journal of Pharmacology and Experimental Therapeutics, 2008)
- Effects of a cardiotonic quinolinone derivative Y-20487 on the isoproterenol-induced positive inotropic action and cyclic AMP accumulation in rat ventricular myocardium: comparison with rolipram, Ro 20-1724, milrinone, and isobutylmethylxanthine. (Journal of Cardiovascular Pharmacology, 1992)
- Design and synthesis of conformationally constrained analogues of 4-(3-butoxy-4-methoxybenzyl)imidazolidin-2-one (Ro 20-1724) as potent inhibitors of cAMP-specific phosphodiesterase (Journal of Medicinal Chemistry, 1995)
- Inhibition of type IV phosphodiesterase by Ro 20-1724 attenuates endotoxin-induced acute renal failure. (Journal of Pharmacology and Experimental Therapeutics, 1996)
- Rat homologs of the Drosophila dunce gene code for cyclic AMP phosphodiesterases sensitive to rolipram and RO 20-1724. (Molecular Pharmacology, 1990)
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SMILESCCCCOC1=C(C=CC(=C1)CC2CNC(=O)N2)OC
-
InChIKeyPDMUULPVBYQBBK-UHFFFAOYSA-N
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